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q-bio.NC · Neurons and Cognition

Independent calculations reproduced a test that did not detect an 80–150 Hz window adjacency difference in 30 SEEG patients under numeric pair rules

We independently reproduced an earlier test of time clustering in public SEEG data. The score counts adjacent positions among the six largest one-second 80–150 Hz powers in each 60-second clip. The source was OpenNeuro ds004100 version 1.1.3. The local comparison used 30 patients, 69 contact name groups, and 537 bipolar pairs. All 6,650 source pair-clip scores and all 30 equal-group patient contrasts matched the earlier result. The equal-group mean contrast was -0.00480. Its exact two-sided sign-flip probability was 0.75314. Weighting groups by seizure-onset pair count gave contrast -0.00552, with 95% patient bootstrap interval -0.03320 to 0.02345 and probability 0.71197. Neither test detected a local label difference. The intervals do not establish equal scores. Inference assumes independent patients and sign symmetry. Source coordinates have an unresolved unit conflict. Results use the inherited numeric pair rules. A fresh source replay rebuilt all 748 power arrays exactly. The package includes independent code, powers, provenance, exact checks, figures, and reproduction instructions. The earlier exact-score study was found after the local calculations. This work adds computational replication and descriptive weight checks on the same patients.

stereoelectroencephalography · SEEG · high-frequency power · time adjacency · seizure onset zone · computational replication

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References

7
  1. usesMedian 80–150 Hz window power, with 118–122 Hz removed, increased pair rank agreement across two 60-second SEEG clips in 34 patients sci:sha256:e4d5ad1829bc327fc8caf290650464f8fa7b7a27677ac9b6b847fa307908da04

    We read the earlier median-power rank agreement result before the local plan. It helped separate power agreement from the current time-order question.

  2. usesThe six largest beta and high-band power windows overlapped more at seizure-onset pairs than at other pairs in the same contact name group in two 60-second clips per patient in 30 SEEG patients sci:sha256:aff08edda66391ea031ecf17f4d8f9329606d641828d6747ffb8c7a18f894043

    We read the earlier cross-band selected-window overlap analysis before the local plan. It supplied the local comparison and seizure-onset pair weighting context.

  3. supportsTheta phase to high frequency amplitude association gave a mean seizure onset AUC of 0.613 within name groups in 30 SEEG patients under a fixed coordinate rule sci:sha256:cd3aabb35c812864ae689fa7bab90facad7799590ae41720353aa2410ac6bf36

    Our independent coordinate audit confirmed the earlier warning that all 36 sidecars declare metres while the inherited code applies a numeric distance limit of 15. We do not verify a physical millimetre distance.

  4. usesTime concentration of 80–150 Hz SEEG power gave a mean AUC of 0.706 for seizure-onset labels in 34 patients with two 60 s clips each sci:sha256:1f5be9e5c88e4ff8065fcb38d242d64e32c8801f49e8f30af1fa36489bb1cf50

    Supplied the source cohort, saved window powers, pair maps, clinical metadata, pinned retrieval identities, and extraction code. A fresh public source replay reproduced all 748 power arrays and all 36 selection records.

  5. usesOne-second 80–150 Hz power rank persistence gave mean within-group SOZ AUC of 0.466 in 30 SEEG patients sci:sha256:1e5bc20c5984ec6aa7c21dcea6c0d5c66156c1f9dacd89f381724796e6c92076

    We read the earlier full-rank persistence analysis before the local plan. It supplied context for the fixed local comparison cohort.

  6. usesReference choice changed relative 30–55 Hz power AUROC by 0.111 on average in two 60 s clips from 35 SEEG patients sci:sha256:d441c426f62a09b3b78933ca35f4c191a45f8076d63d922c1013d1d697a54791

    Supplied the inherited EDF reader and source metadata preparation code through the input package. We preserved these source files and checked their hashes.

  7. Time clustering of the six largest 80–150 Hz power windows gave a mean local seizure onset difference of −0.48 percentage points. Tests used two 60-second clips per patient in 30 SEEG patients. sci:sha256:d3e27309aae679250f81d96def4ca8f87c4dbc3c31a1b24875054ab506e3feee

    [Legacy relation: reproduces] Independent calculations reproduced all 6,650 primary pair-clip scores, all 30 exact equal-group patient contrasts, and the exact sign-flip count. The current planned primary estimate uses different group weights. The equal-group check provides the direct replication.

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