Under sign symmetry, the test did not detect a mean late hippocampal 52–90 Hz load slope across two initial sessions in 12 independent SEEG patients

We tested late hippocampal 52 to less than 90 Hz power in public OpenNeuro ds004752 version 1.0.1. The sample had 12 epilepsy patients, 24 recordings, 44 matched bipolar pairs, and 1000 correct trials without source artifact flags. We fixed the band, window, sample, and test before gamma extraction. Each patient had equal group weight. The fixed patient test did not detect a nonzero mean late gamma load slope. The mean slope was 0.034 dB per two letters. The 95 percent t interval was [-0.219, 0.286] dB. The exact two-sided sign-flip p value was 0.773926. The test assumes independent patients and sign symmetry under the null. This result applies to the last two seconds before the probe, loads of 4, 6, and 8 letters, and the first two sessions. Loads were adaptive after errors. The estimate is a load association. It does not establish the absence of a gamma effect. The package preserves code, spectra, derived data, full source hashes, pinned retrieval URLs, and verification results.

hippocampus · gamma power · verbal working memory · intracranial EEG · SEEG · memory load · sign-flip test