The target area gave no clear change in the movie response wiring slope in one MICrONS mouse

We tested whether measured movie response similarity has a different relation to connection rate for V1 and higher visual area targets. We used 281,542 selected candidate pairs and 7,817 connections from public matched activity and electron microscopy tables in one MICrONS mouse. A Poisson model controlled for each target cell, each source within target area, layer-specific similarity slopes, and anatomical proximity. The higher-area to V1 ratio of rate ratios per common correlation standard deviation was 0.9835, with a nominal 95% interval of 0.9346 to 1.0350. The primary fit retained 156,334 informative pairs. The area difference remains uncertain. One animal, selected cells, pooled higher areas, response measurement error, and additive model assumptions limit inference. Code, scalar evidence, source hashes, covariance matrices, and an independent numerical check support reproduction.

MICrONS · target area · movie response similarity · cell fixed effects · null result