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Shape scores showed no clear mean AUROC gain for uncalibrated sites at 20 to 100 ms in five offline 16-site SEEG tests

We tested whether removal of total waveform size improves detection of a response from an uncalibrated stimulation site. The source was OpenNeuro ds004457 version 1.0.2. Five reused clinical sessions supplied 183 eligible sites and 732 distinct test pulses. Each patient had 100 matched random libraries. The primary test used 16 known sites and 20 to 100 ms voltage. The shape reader had mean AUROC 0.592; voltage distance had 0.584. The difference was +0.008, with a descriptive 95% patient interval of -0.037 to +0.050. The data showed no clear mean detection gain. The shape cutoff accepted 85.3% of uncalibrated responses; voltage accepted 80.1%. Shape scores, labels, and acceptance stayed fixed when complete test vectors had gains of 0.5 and 2. A proof covers positive common gain for nonzero vectors in exact arithmetic. The archive preserves code, contact bins, event roles, all scores, cutoffs, source hashes, a raw retrieval recipe, and three figures. Fresh raw reconstruction and a complete replay matched all saved numeric results. The within-site split is not a global forward time split. This test does not establish a live BCI benefit.

stereoelectroencephalography · electrical stimulation · response recognition · uncalibrated sites · signed cosine · AUROC · common gain

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References

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  1. usesCovariance angles kept 37.9 percent mean site accuracy under nine simulated positive common voltage gains in five offline SEEG sessions sci:sha256:0dbd4e1ba615799ff752cce0c46663f54b7af5ebdf8dd5a55d3ee4cebeb486e4

    Its known-site common-gain test supplies context for the distinction between gain stability and reliable rejection. The new test measures responses from omitted sites. No models or voltages from that package entered this calculation.

  2. usesSixteen site templates gave lower mean AUROC for uncalibrated sites than four at 20 to 100 ms in five offline SEEG sessions sci:sha256:f5697911cac03907598d9499479664aa6de0c82ee46d8dee0a5da9100db87787

    Supplied compact SEEG inputs, fixed readout contacts, input and retrieval code, source hashes, and the voltage baseline. We reproduced its native response-window scores exactly and used the same pulses and libraries for a new shape-score comparison.

  3. usesA signed cosine reader had lower mean site accuracy than a voltage distance reader for recorded 1 mA to 2 mA transfer in three STReEF SEEG patients with eight pairs per patient at 20 to 100 ms sci:sha256:29304cf8fcf5f8bd538895cade5695a3703a4a4fbe1335a7b3367b8500b135e1

    Its recorded-current signed-cosine test supplies context for the limits of scale removal. The new benchmark tests truly uncalibrated sites in another public dataset. No models or voltages from that package entered this calculation.

  4. usesdoi:10.18112/openneuro.ds004457.v1.0.2

    The analyzed recordings and source metadata are from OpenNeuro ds004457 version 1.0.2.

  5. usesdoi:10.1523/JNEUROSCI.1325-22.2023

    This paper describes the source recordings used in the present offline analysis.

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