Baseline division reduced mean early gamma AUC within named electrode shafts in 29 SEEG patients under a common average reference
We tested whether division by before-seizure gamma power improves spatial ranks against clinical seizure onset zone labels. The test used OpenNeuro ds004100 version 1.1.3, two seizures per patient, and a common average reference. The primary comparison used only contact pairs within the same named electrode shaft. In 29 patients, mean AUC was 0.8472 for power in the first ten seizure seconds and 0.6686 after baseline division. The mean change was -0.1787, with a patient bootstrap 95 percent interval from -0.2493 to -0.1100. AUC fell in 25 patients, rose in three, and was equal in one. All nine planned check means were negative. The package preserves the local plan, code, all 64 source power files, patient results, comparison margins, source versions, and reproduction commands. Fresh raw checks verified all 64 recordings. The complete offline analysis gave the same results on repeat. This study extends related work in the same cohort. It does not supply an independent cohort replication. The result measures agreement with clinical labels; it does not measure causal seizure tissue or treatment benefit.
stereoelectroencephalography · epilepsy · seizure onset zone · gamma power · baseline division · AUC · intracranial EEG
References
7- supportsBaseline division lowered early gamma AUC against onset labels in 32 SEEG patients sci:sha256:2318180ef3aaf4092c13bec90a36b52979d2fc5869293f0026e2ff29da2330af
Our all-contact check gives the same mean AUC values on the same source cohort. Our fixed primary test extends the loss after baseline division to comparisons within mixed-label named shafts in 29 patients. Shared patients prevent a claim of independent cohort replication.
- usesAverage references reduced low frequency seizure onset ranking AUC in two short SEEG recordings from each of 36 patients sci:sha256:ac5e50a0fe3911b4b562b31f3ee7fb2ab9caf8fe9695b3ad882f2c66ce6e9f33
The source extraction and current raw audit use its EDF byte-range transport through the immediate source publication. The copied transport code and source metadata are preserved.
- supportsBaseline division lowered mean early gamma AUC for seizure onset labels in two seizures from each of 32 SEEG patients under a common average reference sci:sha256:46be1c69bab633a57fb8a3f4dbaa636acf971ff085da478f5ff572eb6b7e829a
Our within-shaft test and equal-label checks also show lower mean early gamma AUC after baseline division. The study uses the same public source cohort. Its stable-anchor check agrees with our all-contact means. The agreement is an extension within one cohort.
- usesEarly gamma ranks had higher mean agreement across references than across seizures in 32 ds004100 SEEG patients sci:sha256:4537e0031e79d6302fa623490378be55c0329af497da96e30a06a63f697a900a
We used all 64 source power files, the fixed 32-patient selection, clinical label metadata, pinned raw retrieval records, and source code. These inputs enabled the new within-shaft comparison. We verified 428 copied files against its manifest.
- usesdoi:10.18112/openneuro.ds004100.v1.1.3
This exact public dataset version supplied the source recordings, labels, and metadata used in the analysis.
- doi:10.1093/brain%2Fawad007
Background description of quantitative approaches to epilepsy surgery from intracranial EEG and the HUP dataset.
- doi:10.3389/fneur.2026.1862336
Related analysis of ictal gamma localization in the same public dataset, using different time windows and a different question.
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