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q-bio.NC · Neurons and Cognition

Mean and median power selected 61 and 55 SEEG pairs with seizure onset labels at eight pairs per patient in 60 s records A from 36 patients

We tested whether median one-second high-gamma power selected fewer SEEG pairs with clinical seizure onset zone labels than mean power. Public OpenNeuro ds004100 version 1.1.3 supplied 36 epilepsy patients, 3,687 eligible pairs, and two sixty-second records per patient. Each rule selected eight pairs per patient. In record A, mean power selected 61/288 labeled pairs and median power selected 55/288. The equal-patient difference was -2.08 percentage points, median minus mean. The 95 percent patient bootstrap interval was -4.17 to -0.35 points. The exact two-sided sign reference gave p = 0.109375. The bootstrap interval lies below zero, but the exact sign reference gives limited evidence for a decrease across patients. Only seven patients changed label counts. The result does not prove that the rules are equal. Median selection still had 19.10 percent labeled pairs, against 11.59 percent among eligible pairs. The cohort is reused and the local plan is exploratory. Clinical labels and recorded power do not measure BCI information or stimulation safety. The package keeps all per-second powers, native examples, fixed rules, tables, figures, code, source versions and hashes, and repeat commands. All source prefixes, independent spectra, selections, and numerical replay passed their checks.

stereo-EEG · high-gamma power · seizure onset zone · brain-computer interfaces · median estimator · channel selection

Admitted 2 citing publications

References

4
  1. usesA high-gamma to beta power ratio selected fewer SEEG pairs with seizure onset labels in 36 epilepsy patients at eight pairs per patient sci:sha256:dc7d8782523f756be134345c1162e6486484bee59c861611d9c5ac2711595d62

    We used its 36-patient cohort, pair identities, clinical label rule, ten-second powers, source versions, and source records. We extended all 72 prefixes to 60 seconds. All archived ten-second powers matched exactly. The copied inputs passed the archived file manifest.

  2. usesMedian 70–110 Hz power reduced large simulated fault error and brief 90 Hz probe response in two-second SEEG windows from 21 patients sci:sha256:c3df533948fc5bb0164a13d15e22377ce18ffc0c0c84840600ec938376642269

    We used its measured tradeoff between short-fault suppression and short-signal suppression to limit the interpretation of median power. The present study uses recorded interictal power and SOZ labels in a different dataset. It does not establish a neural signal benefit.

  3. Eight SEEG pairs selected by 70–110 Hz power had excess seizure onset labels in 36 epilepsy patients sci:sha256:84f68f3560bb7f223f4749f5296ce18a2349785724480af498da442505265baf

    [Legacy relation: reproduces] Fresh native source prefixes and separate selection code reproduced its eight-pair mean-power result in the first ten seconds: 63 labeled pairs in A and 57 in B. The new median comparison uses 60-second prefixes in the same patients. It is not an independent cohort replication.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The study used the HUP iEEG Epilepsy Dataset, OpenNeuro ds004100 version 1.1.3, for 36 patients and 72 interictal record prefixes.

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