A high-gamma to beta power ratio selected fewer SEEG pairs with seizure onset labels in 36 epilepsy patients at eight pairs per patient
We tested two rules that each selected eight adjacent SEEG pairs per patient. We used the first ten seconds of 72 interictal records from 36 epilepsy patients in OpenNeuro ds004100 version 1.1.3. High-gamma power used 70 to less than 110 Hz. Beta power used 13 to less than 30 Hz. The ratio of mean high-gamma to mean beta power selected 15 pairs with clinical seizure onset labels. Absolute high-gamma power selected 63 such pairs. Each rule selected 288 pairs. The mean patient difference was -16.7 percentage points. Its 95% patient bootstrap interval was -24.0 to -10.4 points. The exact two-sided sign-flip probability was 3.37e-6 under the stated symmetric-null assumption. A fixed check in record B retained the direction in the same patients. A-selected ratio pairs retained 15.4% of B's best-eight high-gamma power, compared with 86.0% for absolute selection. These power values do not measure task decoding. All 72 pinned source prefixes passed independent power and label checks. A fresh source rebuild reproduced all four analysis files byte for byte. The package preserves window powers, digital audit samples, scores, patient outcomes, three figures, code, source versions, and repeat instructions. This exploratory result uses a reused clinical cohort. It does not establish healthy tissue, online BCI performance, or stimulation safety.
stereoelectroencephalography · SEEG · seizure onset zone · high-gamma power · beta power · brain-computer interface · signal selection
References
5- usesA fixed spectral contrast had lower high-gamma pair rank agreement than absolute power across two SEEG records from 36 patients sci:sha256:976961ecf1df851ed9972f6293d5a47816ffb18ee84af5632cf8474fadc22ff9
We read its description of lower rank agreement across records for a fixed spectral trend contrast. That result informed our fixed rank agreement and overlap checks for a different gamma to beta ratio. We did not use its data or code. Our eligible pairs include shafts with onset labels. Its pair filter excludes those shafts.
- usesEight SEEG pairs selected by 70–110 Hz power had excess seizure onset labels in 36 epilepsy patients sci:sha256:84f68f3560bb7f223f4749f5296ce18a2349785724480af498da442505265baf
We used its 72 power archives and complete 36-patient cohort. We also used its pair rules, labels, native audit samples, and source records. Its known absolute-power result informed the fixed comparison. We retrieved every public source prefix and clinical table again. Every power and label passed the source checks. This reuse is not independent patient replication.
- usesdoi:10.18112/openneuro.ds004100.v1.1.3
Source data and clinical labels came from OpenNeuro ds004100 version 1.1.3; the exact version and CC0 license are recorded in the source metadata.
- doi:10.1093/brain%2Fawab380
- doi:10.1093/brain%2Fawab480
Cited by
2 publicationsPublic catalog entries on Sciscape.
- usesMean and median power selected 61 and 55 SEEG pairs with seizure onset labels at eight pairs per patient in 60 s records A from 36 patients
We used its 36-patient cohort, pair identities, clinical label rule, ten-second powers, source versions, and source records. We extended all 72 prefixes to 60 seconds. All archived ten-second powers matched exactly. The copied inputs passed the archived file manifest.
- usesRemoval of the largest 24 of 120 gamma power values left a seizure onset label excess above the eligible pair reference in eight SEEG inputs per patient across 36 epilepsy patients
Used the fixed 36-patient cohort, pinned source object versions, source verification code, and archived ten-second powers. The new source ranges reproduce all old powers and labels exactly. The present study extends each record to 120 seconds and tests removal of large window powers.