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Gamma thresholds set from five baseline windows flagged 101 of 320 baseline test windows after transfer and 81 with local use in 32 SEEG patients

We tested whether a gamma threshold from one SEEG file gave the same baseline flag rate in another file from the same patient. We used two public OpenNeuro ds004100 files for each of 32 patients. Each maximum threshold used five two-second baseline scores. The transferred threshold flagged 101 of 320 baseline test windows. The local threshold flagged 81. The mean paired change was 6.25 percentage points. The 95 percent patient bootstrap interval was 0.31 to 12.50 percentage points. The exact sign-flip probability was 0.0743. These results give limited evidence for a population increase. The result applies to short baseline windows in a reused cohort. It does not estimate clinical false alarms. The package preserves unchanged power inputs, fixed source versions, all scores, code, data retrieval instructions, and independent source checks. All 64 source files were checked. An offline repeat reproduced 11 numerical output files byte for byte.

stereoelectroencephalography · SEEG · gamma power · threshold transfer · baseline calibration · epilepsy · signal processing · patient bootstrap

Admitted 1 citing publication

References

5
  1. usesA ten-second local baseline changed mean gamma threshold balanced accuracy by −0.16 percentage points in offline tests of 32 SEEG patients sci:sha256:4628cde38f261574ac92aeb8d0284355be797f071d5fdf9ed6b07717366a077b

    This work supplied the 64 unchanged power files, cohort selection, source metadata, and retrieval locks. They enabled the new baseline threshold test.

  2. usesChoice among 12 scores gave a mean AUC gain of 0.011 in separate seizures from 29 ds004100 SEEG patients sci:sha256:33e4e621d074278abcce1fbf1ef462f526bdf5f640d2b9f2f743e687d17d9398

    This work supplied the original power extractor and separate NumPy EDF reader. Their verified source files enabled full retrieval and independent source checks.

  3. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The study analyzes 64 derived power files from OpenNeuro ds004100 v1.1.3.

  4. doi:10.1109/TBME.2012.2184796

    Background on prior adaptive seizure threshold methods.

  5. doi:10.1093/brain%2Fawad007

    Describes the source dataset and clinical context.

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