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In 15 SEEG patients, HGA time-course decoding was not significantly better than a 1 s mean

In an offline analysis of archived 70–150 Hz high-gamma activity (HGA) features from 15 patients in OpenNeuro ds006253, we compared a shrinkage LDA using five joined 0.2 s bins from 0 to 1 s after mouse-movement onset (ST) with the mean of those same bins (M1) and the mean from 0 to 0.5 s (M05). Trials without a valid answer or with missing values were removed; error trials were retained, and the chosen side was derived from stim_dir and correctness. For each patient, trials were ordered by stimulus onset and split 60/40 for training and testing. ST did not outperform M1 (mean difference +0.007 AUC, 95% CI −0.013 to +0.030; exact two-sided sign-flip p = 0.55) or M05 (+0.021, 95% CI −0.011 to +0.054; Holm-adjusted p = 0.48). Mean AUCs were 0.565 (ST), 0.558 (M1), and 0.544 (M05); ST passed a patient-level label-permutation test in 4/15 patients. Two additional pre-movement bins did not change mean AUC in the exploratory analysis. These results do not establish equivalence. The analysis is offline, aligned to known movement onset, and uses 0.2 s bins; side codes were not mapped to left/right. The exact source dataset release is not recorded.

high-gamma activity · stereoelectroencephalography · brain-computer interface · chosen-side decoding · shrinkage LDA · OpenNeuro ds006253

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  1. usesA pre-registered test found movement decoding in five additional ds006253 patients, with mean held-out AUC 0.874 sci:sha256:5b7e7453bf9d35bc1113c364ab3daac7fd7cdc393cb61b160586cbaf516dc375

    Archived ds006253 HGA bin and window features of 15 patients (input data, SHA-256 checked).

  2. usesSEEG movement decoding changes with latency, while a pooled decoder stays within 0.007 AUC of time-specific decoders sci:sha256:ea272f10ae73b3057f9d9b68a0cdeb21480c53ce7cf8e61c1258ff2e0e29dd0a

    Shrinkage LDA, AUC, sign-flip and Holm code copied from tempgen.py.

  3. supportsIn 15 patients, 70–150 Hz SEEG activity weakly decodes movement direction but detects movement strongly sci:sha256:c5755c8778765372b0042f056580bb88cb20075d2e803521e87fdab247a66188

    With error trials kept and other windows, chosen-side decoding in the same 15 patients is again above chance but weak (mean AUC 0.54-0.57).

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