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The test did not detect a gain from late power at labelled hippocampal contacts in linear load prediction across two SEEG sessions in 12 patients

We tested public SEEG data from 12 patients with epilepsy. A model used six power bands from 44 matched contact pairs with hippocampal labels in the last two seconds of the memory delay. It learned from the first session and predicted load in the second session. Low load was 4 letters. High load was 6 or 8 letters. The signal model had 51.93 percent balanced accuracy. The trial-order model had 48.50 percent. The mean gain was 3.43 percentage points. The 95 percent t interval was -3.46 to 10.32 points. The exact two-sided sign-flip p value was 0.293945. This test concerns one window and one linear model family. It does not establish absence of a load signal. The package contains code, source records, features, predictions, fitted models, and verification checks.

stereoelectroencephalography · hippocampus · working memory · memory load · cross-session prediction · power spectrum · epilepsy

Admitted 3 citing publications

References

6
  1. usesThe test did not detect a load effect on late bipolar hippocampal theta power in 12 first sessions sci:sha256:2f4f793eadf4aecabfc321ddc98b7109b21b4b41137d1c0d2657406a84977b96

    This work supplies the original first-session sample and timing records. It uses the same first sessions. It is not independent evidence.

  2. usesThe test did not detect a gain from late bipolar hippocampal theta power in linear response time prediction across two sessions in 12 SEEG patients sci:sha256:0a79fe15900ad3463b9a30442d608e3162fcf3445012948ea6caf363c6de5c03

    This work supplies the fixed matched sample, pinned source records, and audited downloader. Its theta table checks the new extraction. The patients are the same.

  3. usesdoi:10.18112/openneuro.ds004752.v1.0.1

    Source recordings for the analyzed first and second sessions; version 1.0.1 is identified in the source records.

  4. doi:10.7554/eLife.78677
  5. doi:10.1126/sciadv.aav3687
  6. doi:10.1038/s41467-025-60681-w

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