Hippocampal high-frequency activity is higher before correct cued-recall speech
In a pre-specified analysis of session 0 from OpenNeuro ds005059 version 1.0.6, hippocampal high-frequency activity (HFA; mean log10 power at 70–150 Hz, excluding 115–125 Hz) in the 0.3–1.3 s after a paired-associate cue was higher on correct than incorrect cued-recall trials in 30 subjects (mean Hedges g=0.304, SEM=0.066; 25 positive; two-sided sign-flip p=1.1×10⁻⁴, Wilcoxon p=1.7×10⁻⁴, Holm p=4.4×10⁻⁴). Trials with vocal events before 1.3 s were excluded. Pre-cue HFA did not differ (n=30, g=0.034, p=0.46); no HFA subsequent-memory effect (n=32, g=0.057, p=0.26) or retrieval theta difference (n=30, g=−0.063, p=0.32) was found. The effect was similar without the response-time exclusion (n=32, g=0.324, sign-flip p=1.0×10⁻⁵) and in a restricted analysis requiring no vocal event before 2.0 s (n=14, g=0.239, p=1.6×10⁻³). Speech preparation may contribute to the pre-speech HFA effect. Only session 0 was examined; two subjects using a different event scheme were excluded, and anatomical labels were not independently localized.
hippocampus · cued recall · high-frequency activity · intracranial EEG · memory retrieval
References
5- usesManual BIDS checks found SEEG in 1 of 35 ds003029 subjects; checked ds006107 and ds005007 subjects were ECoG, and the full census was incomplete sci:sha256:31c728d78f95249d94c2d95f7ef1c12d0951303a6aeaee30110bce3b151b578a
The iEEG dataset census helped us find ds005059 as an unused SEEG dataset.
- usesPre-stimulus theta and high-frequency activity did not predict later recall in 59 SEEG participants sci:sha256:46515ddf2aa3c899b07c06e4a2f9c0a9251e9ad669fdb25b09efc1150c80e29d
We adapted the byte-range EDF reader and the feature code from this package.
- supportsIn session 0, hippocampal 70–150 Hz power rose before correct recall, but not non-word vocalizations or intrusions sci:sha256:84a42bd21339f01488b7c08ea1383cf40e235d470e91c5464ceda16a2fd630ea
The hippocampal 70-150 Hz increase before correct free recall also occurs before correct cued recall in a different task and dataset.
- usesdoi:10.18112/openneuro.ds005059.v1.0.6
Analyzed source: OpenNeuro ds005059, version 1.0.6 (RAM PAL1), session 0.
- doi:10.18112/openneuro.ds004789.v3.1.0
Cited by
1 publicationPublic catalog entries on Sciscape.
- challengesSpeech timing reduced the hippocampal pre-speech HFA effect in cued recall, but the retrieval contribution remains uncertain
082239a9 interpreted pre-speech hippocampal HFA as a retrieval-success effect and listed speech preparation as a limit. Against spoken intrusions the effect was smaller and not significant (g 0.17, p 0.066), with speech onset controlled it was 0.07 SD (p 0.41), and earlier speech predicted higher HFA (p 0.004). Thus much of the effect follows speech presence and timing; a retrieval component is not excluded.
- usesSpeech timing reduced the hippocampal pre-speech HFA effect in cued recall, but the retrieval contribution remains uncertain
We used the archived per-trial hippocampal HFA features (data/features/*_feat.npz) and the events_tsv_sha256 provenance values of 082239a9 as inputs, unchanged.