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q-bio.NC · Neurons and Cognition

The mean 30 to 80 Hz slope contrast was positive for four-step compared with one-step bipolar spans in 33 HUP SEEG patients

We tested whether bipolar contact span changes a fitted spectral slope in public SEEG data. We used two 30-second interictal samples from each of 33 HUP patients. We matched 2,242 contact starts across the two source runs. Each start had five consecutive contact names. The mean patient contrast between spans of four and one contact steps was 0.3421. A patient bootstrap gave a 95 percent interval of 0.2858 to 0.3984. The contrast was positive in all 33 patients after their two run medians were averaged. The fit used 30 to 80 Hz and excluded 55 to 65 Hz. It retained spectral peaks. It was not a separate aperiodic estimate. A common average left bipolar power unchanged but changed the split of the slope contrast into endpoint power and a power ratio. This split does not identify a neural cause that is independent of the reference. Contact steps were name-based proxies, not measured distances. The package preserves spectra, feature tables, code, source pins, results, and reproduction instructions. The result extends earlier public span studies to HUP data.

stereoelectroencephalography · bipolar contact span · spectral slope · intracranial EEG · reference dependence

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References

5
  1. supportsMean fitted 30 to 80 Hz exponents increased from span one to span four in 19 public SEEG records sci:sha256:052b98cf439c64c92e1a606e9f57ad49d05bdd9fdacf92aa263763f1a9280d2d

    The HUP span result agrees in direction with its 19-patient ds003876 result. The current reference audit also shows that the endpoint and ratio allocation changes with a common average. This publication was read after our primary results were calculated. Its result and proof informed the final context; no code or data were reused.

  2. usesThe real cross-spectrum term raises the mean 30–100 Hz SOZ slope contrast compared with summed endpoint powers in two 30-second interictal sections from 35 HUP SEEG patients sci:sha256:67927254e9b250edb71596b40fe59a67f95f756f72af90dba8cbf69d3642788e

    We reused its version-pinned HUP source recipes, 221 metadata files, retrieval manifest, and MIT-licensed EDF reader. We retrieved the public signal ranges again and calculated all span spectra anew. We did not use prior feature arrays. The cohort has prior research exposure.

  3. supportsMedian 30–80 Hz exponents increased with bipolar span from one to four contact steps in two 120-second resting SEEG records sci:sha256:fb15e4e8d41f6df3789930f42f6c9612d96f3a392b0e59462196901374af9154

    We tested its matched-start contact span question in HUP data. The primary mean patient contrast was positive in 33 patients with two 30-second source sections each. The fixed band fit, line exclusion, detrending, and sampling scheme differ, so this is a scoped extension rather than an exact replication.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Public SEEG data and metadata from the exact analyzed OpenNeuro release, version 1.1.3.

  5. doi:10.1088/1741-2552%2Fae1b3b

    Background evidence that intracranial spectral power can depend on bipolar distance and frequency.

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