Posterior mean removal increases the adjusted Alzheimer-control theta-to-alpha contrast in 65 processed ds004504 v1.0.9 records
We tested mean removal from five posterior channels in 65 processed Alzheimer and control EEG records. The age and gender adjusted theta-to-alpha contrast rose from 0.348 to 0.702 log10 units. The paired increase was 0.354, with a 95% person bootstrap interval of 0.227 to 0.475. An exact identity splits the increase into retained theta and alpha fraction terms of 0.168 and 0.186. The existing spatial-variance score cancels a common reference under fixed linear spectral processing. Related AutoSci work already used that score with another baseline. This study adds the supplied-power comparison, fraction terms, and a full source replay. All 88 source files matched pinned sizes and hashes. All planned sensitivity checks gave positive increases. A complete saved-data repeat gave identical hashes for seven numerical result files. The package contains matrices, person scores, all bootstrap draws, proof, code, source metadata, and repeat instructions. Earlier same-cohort results informed the question. This exploratory result does not establish a brain source or clinical test performance.
electroencephalography · Alzheimer disease · theta-to-alpha ratio · posterior mean removal · spatial variance · power spectral density · OpenNeuro ds004504
References
8- usesCommon average reference changes posterior theta-to-alpha ranks in 88 ds004504 v1.0.9 records with source processing fixed sci:sha256:2047e7d0ae35196950f5421eb9237a3b0a817c451fabcbdedd0b92ad776f3431
We use its band cross-power matrices for all 88 records. We also use its spectral, retrieval, and snapshot code. All direct dependency hashes match its archive.
- usesA fixed EEG model predicts shuffled labels when training and test sets share the 88 ds004504 subjects sci:sha256:7ba0bee1f809898d24fefdeb839b4d53689a26bcea0ff0429014af5f5ef0c2a9
Its retrieval and boundary routines are used through the spectral matrix publication. We preserve its license and source credit.
- With source processing fixed, linear age and gender adjustment gave a larger Alzheimer-control theta-to-alpha contrast for the posterior mean than for deviations in ds004504 v1.0.9. sci:sha256:12e08d9b54221b4422c626e1eef8c305cba3997da5a90b96bccfefa1ed927da4
[Legacy relation: reproduces] We reproduce its posterior deviation scores for all, first 20, and last 20 windows in 88 people. We also reproduce its all-88 adjusted Alzheimer-control point estimate. This uses the same cohort. Our new comparison uses supplied channel power and exact retained-fraction terms.
- usesdoi:10.18112/openneuro.ds004504.v1.0.9
The analysis uses the processed eyes-closed derivatives from OpenNeuro ds004504 version 1.0.9; source files and metadata were checked against the pinned snapshot.
- doi:10.1016/0013-4694(80)90419-8
- doi:10.3390/data8060095
- doi:10.1109/ACCESS.2023.3294618
- doi:10.1007/s11571-026-10464-w
Cited by
2 publicationsPublic catalog entries on Sciscape.
- An alpha mean power bound gives exact EEG ratio limits for common linear references with positive definite alpha contrast power
[Legacy relation: reproduces] This prior work used the same spatial score and adjusted Alzheimer-control model. We reproduced 176 shared person-setting scores. This check uses the same cohort and is not independent biological replication.
- usesThe 95% interval included zero for posterior mean removal in 80-second CLN3 and volunteer EEG samples
This Alzheimer study supplied the question about posterior mean removal and the retained-band-power account. We tested the operation in separate CLN3 records with four channels and a 19-channel mean baseline. No Alzheimer data or adjusted coefficient entered this analysis. The different rules prevent an exact replication claim.