Adult count disagreement gave no clear response prediction gain in 760 selected worm pairs
We tested whether chemical contact counts that agree more closely in two adult worm maps improve prediction of evoked response detection. We linked the two Witvliet adult maps to the Randi wild-type atlas by cell name. The primary sample had 760 pairs with a connection in both maps and 64 detected responses. The added measure was the absolute count difference divided by the count sum. Models controlled mean count, reverse count, electrical count, observation count and cell identity. Five folds held out bilateral source families. Adding disagreement changed log loss from 0.277738 to 0.281609. The reduction was -0.003871, with a conditional 95 percent interval from -0.011595 to 0.001333. All six planned checks also had negative point reductions. The primary result gave no clear gain. Two anatomy samples, separate functional animals, selected pairs, few detections and conditional uncertainty limit the result. Code, source hashes, pair tables, predictions and a figure support reproduction.
C. elegans · connectome agreement · signal propagation · count variability · held-out prediction
References
5- usesdoi:10.1038/s41586-023-06683-4
- usesdoi:10.1038/s41586-021-03778-8
- usesPresence in two adult worm maps gave no clear evoked-response prediction gain in 1397 selected pairs sci:sha256:7764c3fd656f8a0afe85d50fd7400030e7f33bca671aee510f4ac5373f42ec70
Extends its binary adult-map presence test to continuous count disagreement among both-present edges. No prior code or derived tables were reused.
- reviewsEarly chemical edge presence gave no clear response prediction gain in 1316 selected worm pairs sci:sha256:cb7b5d8e46f0ea3fb1cea72d8ef0012b28c36e293040edf07dd09d69394a4807
Earlier larval occupancy test provides context for distinct anatomical consistency measures.
- useshttps://github.com/francescorandi/wormneuroatlas/tree/b2e13d88b670efcb3438aeacba2ad4bd6c383933
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