The gamma difference from onset to 10–30 seconds after seizure end gave mean within-shaft SOZ AUC 0.833 versus 0.747 for onset increase in 29 SEEG patients

We tested a fixed gamma difference in 64 public seizures from 32 SEEG patients in OpenNeuro ds004100 version 1.1.3. The score compared the first ten seconds of seizure onset with 10–30 seconds after seizure end. It equals onset increase plus post-seizure decrease, so the baseline cancels. No score weights were fitted. In 29 patients with mixed-label shafts, mean clinical SOZ AUC was 0.833 versus 0.747 for onset increase. The mean gain was 0.086. Its patient bootstrap 95% interval was 0.019–0.160. The primary sign-change p value was 0.023524 under an independent, symmetric patient null. The bootstrap population claim assumes independent, exchangeable patients. Fourteen patients improved, seven worsened, and eight tied. The median gain was zero. The gain interval included zero without shared contacts and with the late period. Added value over post-seizure decrease alone remained uncertain. Mean score rank agreement across two runs was 0.536 versus 0.363 for onset increase. This work reuses a known cohort and does not test surgical outcome. All 64 source records were retrieved again. All feature arrays and 320 range hashes matched the earlier package. The package preserves code, data, source pins, metadata, results, figures, checks, and reproduction instructions.

stereoelectroencephalography · seizure onset zone · gamma power · intracranial EEG · AUC · within-shaft ranking · postictal activity · repeat agreement