Lower contact numbers gave higher mean seizure onset label AUC than higher gamma fractions in two 60-second SEEG samples from 36 patients
We tested whether contact numbers rank clinical seizure onset labels better than relative gamma power. The main comparison used 4,250 matched good contacts in 36 patients from OpenNeuro ds004100 version 1.1.3. Each patient supplied two first-minute interictal samples. Smaller contact numbers and higher gamma fractions were fixed positive score directions. Gamma used common average reference. Mean patient AUC was 0.671 for number and 0.482 for gamma. The mean paired difference was 0.189, with a 95 percent patient bootstrap interval of 0.094 to 0.284. Number AUC was higher in 28 patients. Within electrode name groups, the mean difference was 0.181 in 34 eligible patients. Contact names did not establish physical depth or electrode type. Checks that removed names with uncertain meaning gave a similar main comparison. These checks were exploratory and did not recompute the signal reference. Independent rank-sum AUC checks and a repeated analysis passed. Fresh source prefixes and a separate spectral calculation reproduced 432 gamma scores in one patient. This is a metadata benchmark in one clinical cohort. It does not establish clinical usefulness. The package preserves code, source records, features, patient results, figures, licenses, and retrieval instructions.
stereoelectroencephalography · seizure onset zone · contact number · gamma power · area under the curve · clinical labels · common average reference · patient bootstrap
References
4- usesMatching contacts by name group reduced slow power AUC for seizure-onset labels in 30-second SEEG clips from 24 patients sci:sha256:5c45a9c4687c91d299a386e3d4190ce7597ef78e121f53372be7743edf88e921
The earlier name-group comparison helps interpret the same-prefix AUC and its selected comparison set. The present study uses a different feature comparison, sample length, and 36-patient contact set.
- Mean relative gamma rank correlation is 0.847 and seizure onset AUC is 0.482 in first-minute SEEG pairs from 36 patients after common average reference sci:sha256:cbcb0dd859110de5e9d134af0b072b35567465199e4e4c2bea1b9ab8444fb574
[Legacy relation: reproduces] Before the name exclusion, every archived patient gamma AUC is reproduced exactly from the contact features. A separate spectral implementation reproduces 432 gamma scores from fresh prefixes for one patient. This is computation verification, not an independent cohort replication.
- usesMean relative gamma rank correlation is 0.847 and seizure onset AUC is 0.482 in first-minute SEEG pairs from 36 patients after common average reference sci:sha256:cbcb0dd859110de5e9d134af0b072b35567465199e4e4c2bea1b9ab8444fb574
The study uses the archived contact features, pinned source metadata, EDF decoder, and signal retrieval recipe. These files enable the fixed number versus gamma comparison in all 36 patients.
- usesdoi:10.18112/openneuro.ds004100.v1.1.3
The study uses source metadata and signal prefixes from OpenNeuro ds004100 version 1.1.3; the recorded dataset metadata gives this exact version DOI and CC0 license.
Cited by
7 publicationsPublic catalog entries on Sciscape.
- usesLinear contact number adjustment reduced the mean SOZ slope contrast within name groups in 30 to 100 Hz common average SEEG spectra from 29 patients
Its result showed that contact number carries SOZ label information in this source dataset. This evidence motivated the number term in the new within-group slope models.
- usesSix CAR spectrum features increased mean seizure onset label AUC beyond contact numbers in fixed logistic tests that excluded each of 31 public SEEG patients
Its contact number result motivates the signal comparison. We use the terminal contact integer as a baseline and add a normalized position feature. We do not reuse its spectrum tables or its 36-patient sample.
- usesName group removal preserved more top high gamma contacts than file changes in 32 HUP SEEG patients
Its naming audit identified HUP142 and HUP166 as uncertain name cases. We used that result to fix primary exclusions before new signal extraction. We included both patients in a planned sensitivity check.
- usesFive spectral bands increased mean AUROC for SOZ labels beyond contact numbers in patient holdout tests of 30-second SEEG from 31 patients
The earlier result motivated the contact-number comparator and the check that omitted HUP142 and HUP166. Its 60-second features were not model inputs. The new test used 30-second source spectra with patient-separated fitting and penalty selection.
- usesSix CAR spectral features raised mean seizure onset label AUC beyond contact number. Fixed logistic tests excluded each of 31 SEEG patients.
Its contact number result motivated the fixed metadata comparator. Its source name audit motivated the planned exclusion of HUP142 and HUP166. We imported no model scores from this study.
- usesSix CAR spectrum features increased mean seizure onset label AUC beyond contact numbers in fixed logistic tests that excluded each of 31 public SEEG patients
Its contact number result motivates the signal comparison. We use the terminal contact integer as a baseline and add a normalized position feature. We do not reuse its spectrum tables or its 36-patient sample.
- usesAdding six spectrum features increased mean SOZ label AUC for a contact number model in nested CAR logistic tests of 31 ds004100 SEEG patients
Its finding that contact numbers can rank clinical seizure onset labels motivated the five-feature number baseline. The new study fits its own models and does not reuse the earlier scores.