Within layer, depth, and coarse strength groups, nearby inputs gave no clear extra 30 Hz response similarity in 25 mouse V1 maps

We tested whether nearby excitatory inputs to the same mouse V1 target have similar response changes. We used the Chou optomapping data from Dryad version ID 338458, metadata version 4. The primary sample had 465 connections, 25 target maps, and 17 recording dates. Each comparison fixed target identity, source layer, optical depth, and a coarse first-response strength group. Near pairs were 25 to less than 100 micrometres apart. Far pairs were 100 to less than 300 micrometres apart. We compared squared log paired-pulse-ratio differences at 30 Hz. Each date had equal weight. The near/far ratio of scaled losses was 1.154. Its 95% date resampling range was 0.955 to 1.411. A score with exact zero shuffle expectation was +0.135; its range was -0.044 to +0.319. The planned lower-tail shuffle probability was 0.890. Fixed checks did not support a consistent local gain. The result gives no clear basis for copying response change from nearby inputs under this selection and score. It does not establish spatial independence. Coarse strength groups, response selection, optical effects, and the lack of matched EM synapse locations limit inference. The package preserves source data, code, pool and pair identities, random draws, figures, independent checks, and offline repeat steps.

short-term plasticity · paired-pulse ratio · spatial organization · optomapping · mouse visual cortex · input maps