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Fixed 50 percent shrinkage raised the mean later beta coupling score over a single bipolar pair after a 20 second fit in 19 selected SEEG patients

We tested fixed diagonal shrinkage on public SEEG from 19 selected epilepsy patients. Each fit used 20 seconds. The test used a separate minute. The score measured how well the fitted beta phase relation repeated. The mean score was 0.06125 for 50 percent shrinkage and 0.05110 for the strongest single bipolar pair. The mean gain was 0.01015. Its 95 percent patient bootstrap interval was 0.00382 to 0.01833. Fourteen patients had a positive gain. The interval assumes independent patient sampling. The cohort was selected and previously inspected. The population inference is exploratory. Fresh public byte ranges exactly reproduced all Fourier inputs. An independent solver checked all 34,102 main cells. A second run reproduced the arrays and inference. The package preserves code, inputs, fitted weights, source hashes, and retrieval instructions. The result does not prove true brain connections or clinical benefit.

SEEG · intracranial EEG · diagonal shrinkage · beta coherency · signal processing · epilepsy

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References

4
  1. usesSample rank forced 92.8 percent of unrestricted complex canonical beta coherence scores to one in selected 20-second SEEG samples from 19 patients sci:sha256:32fd9b2dcef61781cc6d5987c2db0808052487e232705a6208abd3c87ce55a3c

    We used its complete 19 patient Fourier inputs, quality checks, source provenance, and public retrieval code. Its sample rank result motivated this fixed shrinkage comparison. We calculated new scores on a separate minute with frozen weights and phase.

  2. usesdoi:10.18112/openneuro.ds003876.v1.0.2

    The analysis used OpenNeuro ds003876 version 1.0.2; the source records identify this exact version and its dataset DOI.

  3. doi:10.1038/s41593-021-00901-w
  4. doi:10.1101/2021.10.15.464594

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