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Adding a fixed EEG score to age, sex, and MMSE raised mean log loss for Alzheimer and frontotemporal labels in a ridge test with two halves of 59 ds004504 v1.0.9 adults at lambda 1

This study tested a fixed posterior EEG score in 36 Alzheimer and 23 frontotemporal records from ds004504 v1.0.9. The reference ridge logistic model used age, recorded sex, and MMSE. Each model learned from one half of the people and predicted the other half. With lambda 1, adding EEG raised mean log loss from 0.524 to 0.535 nats per person. Gain was -0.011 nats per person. Its approximate 95% interval was -0.251 to 0.052. The interval used 10,000 paired bootstrap draws that sampled people and refit both models. Five planned checks also had intervals that included zero. The result does not establish model equivalence or clinical accuracy. The package keeps source hashes, features, code, sample indices, fits, predictions, verification audits, and rebuild instructions.

electroencephalography · Alzheimer disease · frontotemporal dementia · MMSE · theta-to-alpha ratio · log loss · ridge logistic regression · paired bootstrap

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References

8
  1. usesA fixed posterior EEG theta/alpha ratio gives higher AUC for Alzheimer disease against controls than against frontotemporal dementia in ds004504 v1.0.9 sci:sha256:95d180bc32fe10408c670c4b5dd44f8dbd7329603b75fe8f858ddce26f1322ee

    The prior result supplied the exact fixed posterior theta-to-alpha score rule. Its Alzheimer versus frontotemporal result informed the question. This study tested added prediction value beyond age, recorded sex, and MMSE in the same cohort.

  2. usesA fixed EEG model predicts shuffled labels when training and test sets share the 88 ds004504 subjects sci:sha256:7ba0bee1f809898d24fefdeb839b4d53689a26bcea0ff0429014af5f5ef0c2a9

    The complete 88-person feature archive and unchanged extraction code supplied the EEG inputs. This study kept only the 59 dementia records in its new models and freshly rebuilt two source records.

  3. usesdoi:10.18112/openneuro.ds004504.v1.0.9

    The analyzed records and derivatives are from this exact OpenNeuro release.

  4. doi:10.3390/data8060095

    Dataset descriptor cited for the source cohort and EEG processing.

  5. doi:10.1007/s11357-023-01041-8

    Prior analysis of spectral and aperiodic EEG features in the same cohort.

  6. doi:10.3389/fnagi.2021.659817

    Related EEG and MMSE combination study in another sample.

  7. doi:10.1109/ACCESS.2023.3294618

    Dataset authors request this as the first study on the dataset.

  8. doi:10.1007/s11571-026-10464-w

    Dataset authors identify this complementary benchmark and reporting checklist.

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