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The late memory theta phase load test did not reject zero after correct prior responses in 14 SEEG patients under sign symmetry

We tested whether memory load changed event-aligned theta phase consistency at hippocampus-labelled SEEG contacts. We used OpenNeuro ds004752 version 1.0.1. The fixed sample had 14 patients with epilepsy, 28 sessions, and 95 anchor contacts. We compared eight letters with four letters in the last two seconds before the probe after a correct prior response. The mean contrast was -0.005596 pairwise phase consistency units. The 95 percent patient bootstrap interval was [-0.013441, 0.002736]. The exact two-sided patient sign-flip test gave p = 0.211670. It did not reject zero at 0.05. This test requires independent patients and symmetric effects under the null. It does not prove that the effect is absent. The package preserves complex Fourier features, source hashes, code, result tables, random draws, figures, and raw retrieval instructions. Full source hashes, independent numerical checks, one fresh raw rebuild, and a repeat analysis passed.

pairwise phase consistency · theta phase · intracranial EEG · verbal working memory · hippocampus · memory load

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References

6
  1. usesUnder patient sign symmetry, theta load tests did not reject zero under two references at hippocampus-labelled SEEG contacts in 14 patients sci:sha256:fe031d2cf5056a40d155878f7189a85f1b757d3dd4e82af588b3c02186d20b5a

    This publication supplied the fixed first-two-session and hippocampus anchor selection, pinned metadata and raw manifest, metadata checker, EDF reader, and small raw audit file used to build and validate the new phase features.

  2. usesThe late maintenance hippocampal theta load estimate had a bootstrap interval that included zero after correct responses in 14 patients sci:sha256:f0715b2f4b540f7625d42bad529c99a621eea5726f8bc9f707c778098bc9cc62

    This prior power analysis supplied the task-history reason for conditioning on a correct prior response and the pinned task timing record. The task code hash was checked again. The present publication tests a new phase measure.

  3. usesdoi:10.18112/openneuro.ds004752.v1.0.1

    Source data: OpenNeuro ds004752 version 1.0.1, matching the fixed Git commit, file hashes, and object versions used in this analysis.

  4. doi:10.7554/eLife.78677
  5. supportsdoi:10.1038/s41597-020-0364-3

    This paper states the task-history rule that an error was followed by four letters; the publication reports eight exceptions in the selected metadata.

  6. supportsdoi:10.1016/j.neuroimage.2010.01.073

    Defines pairwise phase consistency, the measure used for the phase estimates.

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