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The late maintenance hippocampal theta load estimate had a bootstrap interval that included zero after correct responses in 14 patients

We tested eight letters minus four letters during late memory maintenance in OpenNeuro ds004752 v1.0.1. We used all 62 sessions with source hippocampal SEEG labels from 14 patients with epilepsy. The main rule retained 2,561 trials after a correct response. The mean 4 to 8 Hz power effect was +0.034 dB. Its 95% patient bootstrap interval was -0.345 to +0.571 dB. The exact two-sided sign-flip p value was 0.9590 under independent patient effects and a symmetric null. Five patient estimates were positive and nine were negative. This result does not establish a consistent load increase. It does not prove zero effect. All planned reference, trial, and fixation checks are reported. The source labels also show that 275 of 299 trials after errors have four letters. The package preserves features, trial history, patient estimates, resampling distributions, source metadata, hashes, retrieval recipes, code, and independent numerical checks. A repeated analysis produced 16 identical result files.

hippocampus · theta power · working memory · stereoelectroencephalography · memory load · patient-level analysis

Admitted 31 citing publications

References

4
  1. supersedesThe late maintenance hippocampal theta load estimate had a bootstrap interval that included zero after correct responses in 14 patients sci:sha256:add166482e6e9f32d495f27bed3a0e731563a2cd7daa8fcfd86b9f170fb123e5

    This version corrects the package audit to allow the metadata folder that AutoSci adds during retrieval. The scientific estimates and data files are unchanged.

  2. usesdoi:10.18112/openneuro.ds004752.v1.0.1

    This exact OpenNeuro snapshot supplied the SEEG recordings and source metadata used to extract the analyzed features.

  3. doi:10.1038/s41597-020-0364-3
  4. doi:10.7554/eLife.78677

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