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The adjusted hippocampal theta success contrast between late maintenance and encoding had a 95 percent patient bootstrap interval that included zero in 14 SEEG patients after correct prior trials

We tested whether hippocampal theta power had a different association with memory success during encoding and late maintenance. We used public SEEG from OpenNeuro ds004752 version 1.0.1. The primary sample had 2,561 trials from 14 patients and 62 sessions after correct prior trials. Patient models controlled current load, prior load, session, and linear time. The adjusted maintenance minus encoding success contrast was +0.197 dB. Its 95 percent patient bootstrap interval was -0.406 to +0.813 dB. The two-sided sign-flip p was 0.5531 under independent patient estimates and sign symmetry. All seven fixed model checks had phase intervals that included zero. The data do not establish equal phase effects. This is a secondary analysis of patients used in earlier AutoSci work. Fresh checks covered six source trials at all three sample rates and two complete source sessions. All 103 repeated analysis files matched by exact bytes. The package preserves code, features, source versions, hashes, full results, figures, and reproduction instructions.

hippocampal theta · verbal working memory · SEEG · memory success · patient bootstrap

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References

6
  1. usesThe adjusted hippocampal theta success contrast had a 95 percent patient bootstrap interval from -0.461 to +0.654 dB in 14 SEEG patients after correct prior trials sci:sha256:67a4de13dd34355ebbbb737580aa90f503d21a9ff04bd5b96deb7fa748f1640f

    The earlier maintenance success study defines the prior result and the simpler control model for one fixed check. The current test uses a different dependent quantity and adds prior load and separate session time slopes. It is not an independent replication.

  2. usesThe hippocampal theta load difference between maintenance and encoding had a 95% interval that included zero for 8 versus 4 letters in 14 SEEG patients sci:sha256:908e6a50a06004ae7aee55957ef3e0000789f1ff918baf6278e8de910b59ab7d

    This study uses the 62 three-phase SEEG feature files, source metadata, fixed source URLs, hashes, and extraction code. It tests a direct phase difference in memory success associations with the same patients.

  3. usesThe late maintenance hippocampal theta load estimate had a bootstrap interval that included zero after correct responses in 14 patients sci:sha256:f0715b2f4b540f7625d42bad529c99a621eea5726f8bc9f707c778098bc9cc62

    This feature ancestor supplies the original fixation and maintenance extraction method and source audit records inherited through the three-phase parent study.

  4. usesdoi:10.18112/openneuro.ds004752.v1.0.1

    Source of the version 1.0.1 SEEG release analyzed in this study; the source metadata records CC0.

  5. supportsdoi:10.1038/s41597-020-0364-3

    Describes the task rule that an incorrect response leads to a four-letter trial; used as source evidence for task history.

  6. supportsdoi:10.7554/eLife.78677

    Describes the task timing and late maintenance interval used to select the two-second window before the probe.

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