The sign-flip test did not reject zero hippocampal theta probe contrast in slow correct trials from 14 epilepsy patients with independent effects and a symmetric null
This public SEEG study compared probes outside and inside a remembered letter set. It used 1277 slow correct trials from 14 epilepsy patients and 62 sessions. The outcome was the change in hippocampal 4-8 Hz power from the second before the probe to the second after it. The adjusted outside-minus-inside patient mean was -0.320 dB. The 95% patient bootstrap interval was [-0.599, -0.038] dB. The exact patient sign-flip test gave p=0.0515. The primary test did not reject zero at the fixed 0.05 threshold. The descriptive bootstrap interval excluded zero. These two procedures need not agree. The interval does not override the fixed test. The result does not establish equal responses. The sign-flip test assumes independent patient effects with a symmetric null. The trial selection and response preparation limit the interpretation. The package includes fixed source versions, new signal features, code, all patient results, and independent checks.
intracranial EEG · hippocampus · theta power · working memory · recognition probe · patient sign-flip test · epilepsy
References
4- usesThe late maintenance hippocampal theta load estimate had a bootstrap interval that included zero after correct responses in 14 patients sci:sha256:f0715b2f4b540f7625d42bad529c99a621eea5726f8bc9f707c778098bc9cc62
This study used the fixed source list, complete raw object hashes, metadata, task timing lock, and original EDF helper. It checked the new reader against the earlier maintenance features. The new probe outcomes were extracted from the raw source. The patient cohort is shared.
- usesdoi:10.18112/openneuro.ds004752.v1.0.1
The analysis used 62 sessions of source recordings from OpenNeuro ds004752 version 1.0.1; the saved source locks identify the retrieved objects.
- doi:10.7554/eLife.78677
- doi:10.1038/s41597-020-0364-3
Cited by
2 publicationsPublic catalog entries on Sciscape.
- usesSelecting slow correct responses increased the estimated hippocampal theta contrast before the probe in 14 epilepsy patients under independent effects and a symmetric null
This study reuses unchanged hippocampal band and spectral features, source metadata, pinned raw retrieval code, and extraction receipts. It adds a paired comparison between slow correct and all correct response rules.
- usesSelecting slow correct responses increased the estimated hippocampal theta contrast before the probe in 14 epilepsy patients under independent effects and a symmetric null
This study reuses unchanged hippocampal band and spectral features, source metadata, pinned raw retrieval code, and extraction receipts. It adds a paired comparison between slow correct and all correct response rules.