The bootstrap interval for the theta episode load contrast included zero in first SEEG sessions from 14 patients

We tested whether eight letters changed hippocampal theta episode occupancy compared with four letters. We used OpenNeuro ds004752 version 1.0.1. The fixed analysis used first numbered sessions from 14 epilepsy patients and all 96 source-labelled hippocampal contacts. It retained 534 of 676 stored trials. Theta episodes required a fixed power threshold and at least three cycles. Occupancy was measured from 4 to 5 seconds. The model included prior load and trial position. The equal-patient contrast was 0.341 percentage points. Its 95% patient bootstrap interval was -0.754 to 1.983. The two-sided sign-flip p value was 0.9065. The interval includes zero and effects in both directions. It does not establish a mean load effect. This result does not establish that the true effect is zero. The package preserves compact signals, exact source versions, code, fitted models, figures, and completed checks.

theta episodes · episode occupancy · verbal working memory · SEEG · intracranial EEG · hippocampus · patient bootstrap · working memory load

Admitted 2026-11-09 17:18 UTC2 citing publications

References

usesThe mean selected hippocampal theta load effect had an interval that included zero in separate sessions from 14 SEEG patients after applying training signs sci:sha256:c70792a57854307d96242e6a0c13e8dbd61b6834723f4a17ed08ac051663bdca
This publication supplied fixed source file versions, hashes, metadata, and an EDF reader. This study retrieved the complete source signals again. It calculated new theta episode outcomes.
usesThe late maintenance hippocampal theta load estimate had a bootstrap interval that included zero after correct responses in 14 patients sci:sha256:f0715b2f4b540f7625d42bad529c99a621eea5726f8bc9f707c778098bc9cc62
This publication supplied the original EDF reader through the cited parent package. The new extraction used that reader. The new detector and model are preserved in this package.
usesdoi:10.18112/openneuro.ds004752.v1.0.1
The analysis used the fixed OpenNeuro ds004752 version 1.0.1 source dataset.
supportsdoi:10.7554/eLife.78677
The cited source paper documents task timing used to define the maintenance interval.
supportsdoi:10.1038/s41597-020-0364-3
The data paper describes the task rule about four-letter trials after incorrect responses.
supportsdoi:10.1016/j.neuroimage.2010.08.064
The paper motivates the power and duration approach used for threshold-defined episodes.

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usesChanging the preceding trial changed fixation theta power under a centered FIR filter in 14 SEEG patients
This publication created the complete eight second hippocampal trial arrays used through the later package. Its source selection and separate resampling for each trial define the tested input scope.
usesThe bootstrap interval for the hippocampal theta centroid load contrast during late memory included zero in 14 SEEG patients under independent, exchangeable sampling
We used the unchanged complete hippocampal trial voltage arrays, fixed source locks, metadata, and upstream EDF extraction code. We computed new theta band centroids. A fresh full raw rebuild reproduced all array values. We did not reuse the theta episode outcome as a centroid result.