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Mean hippocampal fixation theta was lower after errors at load four in epilepsy patients with session and prior load controls

We tested hippocampal fixation theta after errors and correct responses in public SEEG from OpenNeuro ds004752 version 1.0.1. The selected sample had 14 patients with epilepsy, 60 sessions, and 745 trials at current load four. Each patient model controlled for session, preceding load, and linear trial position. The mean after-error minus after-correct contrast was -1.441 dB. The 95 percent patient bootstrap interval was -2.044 to -0.892 dB. The exact two-sided patient sign-flip p value was 0.000244, under independent patient effects and a symmetric null. Thirteen patient estimates were negative. All planned sensitivity means were negative. The late maintenance interval included zero. A positive maintenance-minus-fixation contrast shows how baseline history can enter a later change. The result is a conditional association. It does not isolate a causal error response. Fresh public raw ranges checked 60 sessions with an independent reader and spectrum calculation. An offline run reproduced 111 result files exactly. The package preserves code, feature data, source metadata, versions, hashes, model fits, results, figures, and repeat instructions.

hippocampus · theta power · SEEG · working memory · fixation · response error · patient bootstrap · epilepsy

Admitted 6 citing publications

References

6
  1. usesThe adjusted hippocampal theta success contrast had a 95 percent patient bootstrap interval from -0.461 to +0.654 dB in 14 SEEG patients after correct prior trials sci:sha256:67a4de13dd34355ebbbb737580aa90f503d21a9ff04bd5b96deb7fa748f1640f

    We read its current response success study after our primary effect. It supplied context for a different outcome contrast in the same patients. This study tests preceding outcome during the next fixation.

  2. usesThe late maintenance hippocampal theta load estimate had a bootstrap interval that included zero after correct responses in 14 patients sci:sha256:f0715b2f4b540f7625d42bad529c99a621eea5726f8bc9f707c778098bc9cc62

    We used its 62 SEEG feature archives, source metadata, exact raw object versions, full hashes, and extraction code. We tested a new preceding-error contrast at current load four.

  3. usesAfter correct responses, fixation theta power was lower after eight than four letters in 14 SEEG patients with the stored reference and linear trends sci:sha256:4b939563159f2dd8e44b9daadad0fd1612e225bb316937e9d3a741f741316571

    We read its preceding-load result after our primary effect. It supplied context for fixation history dependence. Our model held preceding load fixed and tested preceding response outcome.

  4. usesdoi:10.18112/openneuro.ds004752.v1.0.1

    The analysis uses SEEG feature data derived from OpenNeuro ds004752 version 1.0.1.

  5. doi:10.1038/s41597-020-0364-3
  6. doi:10.7554/eLife.78677

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