The late maintenance 13–30 Hz hippocampal beta load contrast had a bootstrap interval that included zero in 14 SEEG patients after correct prior responses

We tested a memory load contrast in public SEEG data from OpenNeuro ds004752, snapshot 1.0.1. The analysis used 14 patients, 62 sessions, and 2,561 trials after correct prior responses. It compared eight letters with four letters. The outcome was the change in hippocampal 13–30 Hz power from fixation to late maintenance. Patient models controlled session, time within each session, and previous load. The equal-patient mean was +0.087 dB. The 95% patient bootstrap interval was −0.368 to +0.601 dB. The exact patient sign-flip p value was 0.7603, under independent patients and a symmetric null distribution. All planned sensitivity intervals included zero. The data do not prove a zero effect. The package preserves the plan, source features, trial selections, patient estimates, model inputs, code, figures, numerical checks, and a pinned raw retrieval recipe. Clinical sampling and adaptive trial history limit the result. This is an exploratory adjusted association in the tested task and patient group.

hippocampus · beta power · verbal working memory · SEEG · memory load · patient bootstrap