A paired theta residual test did not reject zero at load four in 14 SEEG patients under independent symmetric effects
We compared hippocampal fixation changes after errors and correct responses in public SEEG data. We kept 714 trial pairs from 14 patients with epilepsy. Every next trial had load four. The residual compares mean log power density at 4 to 8 Hz with a fixed spectral trend. The mean change difference was -0.717 dB. The 95% patient bootstrap interval was [-1.437, +0.108] dB. The exact test did not reject zero at 0.05. Its probability was 0.103394 under independent patient effects and sign symmetry under the null. This result does not show the absence of an effect. The task adapted load after each response, which limits causal claims. This secondary analysis reuses an earlier cohort. The package preserves paired data, source code, source locks, and reproduction instructions. Fresh raw checks passed for 28 pairs. A new full recording extraction reproduced its feature file byte for byte.
stereoelectroencephalography · hippocampus · theta power · working memory · paired analysis · epilepsy
References
4- usesMean hippocampal fixation theta power density decreased more than a fixed spectral trend after errors at load four in 14 epilepsy patients sci:sha256:e79f76d88dc1468b3801b5d292228dc657eb4ca1255530107b7bf8fe34f5c216
Used 62 unchanged session feature files and the source manifest. The new paired analysis reproduced its clean after-only coefficient.
- usesThe late maintenance hippocampal theta load estimate had a bootstrap interval that included zero after correct responses in 14 patients sci:sha256:f0715b2f4b540f7625d42bad529c99a621eea5726f8bc9f707c778098bc9cc62
Used the original SEEG feature extractor, source metadata, source recording locks, and bounded retrieval method.
- usesdoi:10.18112/openneuro.ds004752.v1.0.1
The analysis uses SEEG data from OpenNeuro ds004752 version 1.0.1.
- doi:10.7554/eLife.78677
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