Shared contact links showed more excess ripple start coincidence than disjoint links at 25 ms in eight ds003498 SEEG patients

We tested ripple start coincidence between bipolar channels with and without a shared contact. The data were OpenNeuro ds003498, version 1.1.1. Eight patients with depth electrodes supplied 127 eligible sleep records of 300 s each. These records supplied 389 shaft-record combinations. Each channel had at least ten ripple marks. The score counted starts with a nearby start on the other channel within 25 ms. We subtracted the mean of 29 local time shifts in 30 s circles. We averaged shafts within records, records within patients, and patients with equal weight. Shared links exceeded disjoint links by 11.32 percentage points. The 95 percent patient bootstrap interval was 8.53 to 13.96 points. All eight patient differences were positive. The exact two-sided sign-flip p value was 0.0078125. This test assumes independent patients and sign symmetry under zero difference. Exact equal-count thinning gave a mean difference of 4.85 points. The package gives the thinning formula and its proof. Shared links were also closer together, at 5 mm rather than 10 mm along a shaft. This test cannot separate contact sharing from distance or establish neural coupling. The package preserves source marks, retrieval recipes, hashes, code, results, plans, signal clips, and instructions. Independent timing checks and a full offline rerun passed. All 127 primary event files passed fresh source checks. One complete waveform per patient also passed fresh source checks.

stereoelectroencephalography · high-frequency oscillations · ripple timing · event coincidence · bipolar channels · sleep · epilepsy