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Shared contact links had higher excess STE HFO coincidence than disjoint links at 25 ms in 16 UCLA SEEG patients after equal count thinning

We tested whether links that share a contact have more excess HFO start coincidence than disjoint links in a separate public SEEG cohort. HFO means high frequency oscillation. SEEG means stereoelectroencephalography. We used released STE marks from the first hour of OpenNeuro ds005398 version 1.1.3. The test used 217 consecutive channel triples on 69 shafts in 16 UCLA patients. It balanced counts by exact expected thinning and subtracted rotations in 10 s circular blocks. At a 25 ms limit, the mean difference was 8.96 percentage points. The 95% patient bootstrap interval was 6.87 to 10.77 points under independent, exchangeable patient sampling. Fifteen patient differences were positive. A separate implementation and a complete offline rerun reproduced the primary result. All planned secondary checks had positive mean differences. Shared links were also closer together. This result cannot separate contact sharing from distance or establish neural connectivity. The package preserves source bytes, a fixed plan, code, scores, bootstrap draws, checks, and repeat instructions.

stereoelectroencephalography · high frequency oscillations · event coincidence · shared contact · exact thinning · replication · OpenNeuro

Admitted 2 citing publications

References

4
  1. Shared contact links showed more excess ripple start coincidence than disjoint links at 25 ms in eight ds003498 SEEG patients sci:sha256:91269ef18134a7a327d5a484820b3a2533ed8543583f10cd6adf27aa11797892

    [Legacy relation: reproduces] This separate UCLA cohort test reproduced the positive shared contact excess coincidence direction with exact equal count thinning. It used the previous coincidence method and thinning proof. The detector, joining rule, observation window, block length, and triple support differ. It is a conceptual replication and does not compare effect sizes across cohorts.

  2. usesThe HFO timing AUC change interval included zero within shafts in the first hour of 17 SEEG records under independent, exchangeable patient sampling sci:sha256:e826a66bffb95891e2e26be5f10a7c3c51266f649dcdec1d628b4ae81fedf78e

    The study reused its fixed ds005398 v1.1.3 source archive, manifest, parser, and public retrieval code. A fresh public byte check passed for all 94 needed input files or EDF headers. Its fitted timing models and outcome estimates were not used in this test.

  3. usesdoi:10.18112/openneuro.ds005398.v1.1.3

    The study analyzes released STE event tables and metadata from this exact dataset version.

  4. supportsdoi:10.1111/epi.18545

    This paper describes the source cohort and released event methods used to define the public candidate marks; the present study measures coincidence in those marks.

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