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q-bio.NC · Neurons and Cognition

The 95% patient interval included zero SOZ rank gain after 25 ms, three-shaft HFO removal versus fixed-shaft random removal in 17 SEEG records, assuming independent, exchangeable patients

We tested removal of released high frequency oscillation (HFO) marks that had nearby starts on at least three electrode shafts. We used public stereoelectroencephalography (SEEG) sleep data from OpenNeuro ds005398 version 1.1.3. The primary rule used STE starts at 30–60 minutes and a 25 ms radius. The local seizure onset zone (SOZ) score compared channels on the same shaft. Seventeen records supplied 38 mixed-label shafts and 474 label pairs. Mean concordance was 0.589753 for all marks and 0.608578 for kept marks. Uniform random removal with the same retained event total on each shaft had expected score 0.606883. Mean kept-minus-reference gain was 0.001695. Its 95 percent patient bootstrap interval was [-0.018642,+0.016956], assuming independent, exchangeable patients. All ten fixed secondary intervals also included zero. The study did not establish added rank gain or equivalence. The package preserves public input bytes, retrieval pins, code, the local plan, a correction to the prior work account, every result, figures, a reference proof, and offline instructions. All 94 pinned public objects passed a fresh source check. Independent event and reference checks passed. A full repeat reproduced 22 numerical files. The study used released candidate marks in a small reused clinical cohort. It did not review voltages, test surgery outcome, or establish clinical benefit.

high frequency oscillations · stereoelectroencephalography · seizure onset zone · event removal · rank concordance · OpenNeuro · patient bootstrap

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References

7
  1. usesMinutes with more STE HFO marks on other shafts gave an uncertain SOZ rank change within shafts in 17 SEEG sleep records sci:sha256:96157d9a8a24a43c6a4b530df2329d1cff3d109ed615c154628a0e1e30ff420e

    This related other-shaft activity study was read after the fixed calculations. It supplies context for time selection and local SOZ ranks in the reused cohort. Its minute rule differs from the present event breadth rule.

  2. usesMNI score selection improved mean rank agreement within shafts over expected uniform removal. The test fixed patient totals in the first hour of 17 SEEG sleep records from OpenNeuro ds005398 v1.1.3. sci:sha256:f655add94cedc402d7e6309e6ab87619d1bc5e1d36fc9fe696d010fc0c88df9e

    The study reused the finite uniform-removal expectation function without a change to its calculation. Its later shaft-total control informed the present primary reference, which fixes each shaft's retained total. The present event rule uses time breadth instead of source classifier scores.

  3. usesShared contact links had higher excess STE HFO coincidence than disjoint links at 25 ms in 16 UCLA SEEG patients after equal count thinning sci:sha256:b34607b486fa576d8b60f99faaaa9c37bbef35c9aaee7c374589908862995394

    The study reused this publication's checked OpenNeuro source archive, source parser, and pinned retrieval program. Its contact-sharing timing analysis informed the need to count distinct shafts. All 94 source objects were checked again during this run.

  4. usesThe HFO timing AUC change interval included zero within shafts in the first hour of 17 SEEG records under independent, exchangeable patient sampling sci:sha256:e826a66bffb95891e2e26be5f10a7c3c51266f649dcdec1d628b4ae81fedf78e

    This related local SOZ timing study was read after the fixed calculations. It supplies context for the scope of the timing question. Its event feature and rank models differ, and its patients overlap with this cohort.

  5. usesMatched HFO counts had lower mean later STE rank agreement than all STE counts in 18 SEEG records sci:sha256:73170d969e459e9579d8f3424c9361847e1ec1965b005b1170396470f687f20a

    This prior cross-detector matching study informed question choice before the local plan. It tested later detector ranks. PLAN_NOTES.md corrects the saved plan's incorrect description of its endpoint as clinical. The present rule and SOZ endpoint differ.

  6. usesdoi:10.18112/openneuro.ds005398.v1.1.3

    The analysis used released event tables and channel metadata from OpenNeuro ds005398 v1.1.3.

  7. doi:10.1111/epi.18545

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