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The within shaft high gamma agreement change interval included zero after a six scaled MAD mask in 33 SEEG patients under common average reference

We tested the effect of large low frequency voltage excursions on a high gamma power comparison. We compared 80 to 150 Hz SEEG power with clinical seizure onset labels within named electrode shafts. We used two brief interictal records per patient from OpenNeuro ds004100 version 1.1.3. The primary comparison included 33 patients and 3531 contact pairs across both records. Each onset and other contact pair used the same accepted two second windows. The detector threshold was six scaled median absolute deviations (MAD), with 0.1 second margins. The full comparison used the same eligible pairs. Under common average reference, mean pair agreement was 0.7036 before masks and 0.7031 after masks. The mean change was -0.0005 with a patient bootstrap 95 percent interval of [-0.0073, 0.0075]. The paired patient sign flip test gave p=0.9117. The 95 percent interval for the mean change included zero. The test did not establish a change or equivalence. The recorded reference check showed a small decrease. Its change interval was below zero. The detector had no expert spike labels. This result does not prove that accepted windows contain no spikes. The package preserves source versions, hash checked retrieval, a raw fixture, masks, pair scores, timing controls, code, and offline checks.

stereo-electroencephalography · high gamma power · seizure onset zone · voltage excursions · robust median absolute deviation · matched pair agreement · common average reference · epilepsy

Admitted 2 citing publications

References

6
  1. usesThe within shaft high gamma median minus mean AUC interval included zero in 33 SEEG patients under common average reference sci:sha256:c9e107fad24e8ae4d95f97296875ad86b96b989dc779cd068fbfce8d1147e613

    We used the selected 70 record catalog, pinned source range recipes, metadata, raw EDF fixture, and MIT EDF code. We compared all 994080 new power values with its saved arrays. Its mean versus median result helped select the question. The present masks, shared window scores, and timing controls are new calculations on the same sample.

  2. usesA six scaled MAD mask with 0.5-second margins gave zero median paired theta-gamma dMVL change in two 400-second resting SEEG records sci:sha256:b92724f8b2ff56d577219c14521ec0cde1179913ced16e0ccd0825d8fd5a5723

    We used its voltage mask and matched deletion study as background for detector limits and timing controls. That study tested theta gamma coupling in two ds005670 records. We tested seizure onset labels in ds004100. No code or signal derivatives from that study were used.

  3. usessci:sha256:0572ac7f36f9da69bed263571d583c8b82cffa76bfd0ff04699a77156329aa77 not known to Sciscape

    We used its rationale and name rule for comparisons within electrode shafts. We also used its two record patient aggregation. This rule reduces some location differences between label classes. It does not make anatomy identical.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    This study analyzes the first 60 seconds from two interictal SEEG records per patient in this dataset, including source seizure onset labels.

  5. supportsdoi:10.1093/brain%2Fawab480

    Provides evidence for the background claim that brain location affects intracranial EEG features, motivating within-shaft comparisons.

  6. supportsdoi:10.1016/j.clinph.2009.10.019

    Provides evidence that sharp transients and harmonics can produce apparent oscillations after filtering, motivating a test of voltage excursion masks.

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