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A six scaled MAD amplitude cap increased mean residual map agreement between file excerpts of 1–80 Hz filtered SEEG from 36 patients

This study used public SEEG data from OpenNeuro ds004100, version 1.1.3. It tested two 64 s file excerpts from each of 36 patients with epilepsy. The code formed bipolar signals from adjacent contacts after filtering from 1 to 80 Hz. The primary amplitude cap limited deviations from each block median to six scaled median absolute deviations. The analysis compared correlation magnitude maps after endpoint signal, shaft pair, and log distance controls. Mean agreement was 0.6597 without the cap and 0.6665 with the cap. The mean paired change was +0.0068, with a 95 percent patient bootstrap interval of [+0.0013, +0.0166]. The median change was +0.00054. One patient supplied 68.6 percent of the sum of changes. The second block alone did not establish an increase. These results apply to the short excerpts and fixed method. They do not establish clinical benefit. The package preserves 72 derived files, source versions, hashes, a raw example, code, results, and repeat instructions. An offline repeat produced nine identical result files.

stereoelectroencephalography · SEEG · amplitude cap · median absolute deviation · correlation maps · signal processing · epilepsy

Admitted 11 citing publications

References

6
  1. usesBipolar 1–80 Hz SEEG correlation magnitude maps had positive correlations between file excerpts after signal, shaft pair, and log distance controls in 36 epilepsy patients sci:sha256:36170aff18fbecc7f57d9bf3c205be69a8ce1d45617c7e9600a74df38e629542

    This study used the fixed cohort, layouts, metadata, source byte ranges, EDF reader, and spatial projection method. It retrieved the raw public bytes again. It reproduced the uncapped patient agreement to a maximum absolute error of 4.94e-13 before reporting new amplitude cap results.

  2. usesAfter signal and shaft pair controls, 1–80 Hz bipolar SEEG correlation magnitude between shafts had negative fitted coordinate distance slopes in all 36 tested epilepsy patients sci:sha256:c00ccb31868a25e0564b56ac6efac067acd957bb3bfeb7e0e5f340e3618bbca7

    This publication supplied the original covariance and projection input functions through the direct source study. The package preserves the imported functions and MIT notices.

  3. usesThe within shaft high gamma agreement change interval included zero after a six scaled MAD mask in 33 SEEG patients under common average reference sci:sha256:984de81c89925ac4d31f705200f3fd067ee8a9115807eaca3fee37a5a918f0a5

    Review of this publication summary helped define a separate amplitude sensitivity test. This study retains all time samples and tests map agreement. It does not use the prior gamma or clinical label scores.

  4. usesA median cap changed mean beta phase-lag rank agreement by -0.022 between paired 60-second intervals in 35 SEEG patients sci:sha256:a5499e3191a69630824203781832cacbe2d3ded64c0a892ecef2857e242a89c4

    Review of this beta phase-lag cap study helped define a separate question about voltage amplitude and between-file agreement. Its capped cross-spectrum results were not used as numeric inputs.

  5. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analysis used HUP iEEG Epilepsy Dataset version 1.1.3; the saved source metadata and exact-version evidence identify this DOI and CC0 terms.

  6. doi:10.1088/1741-2552%2Fac90ed

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