The IED and recall-classifier protocol produced no data results because downloads stalled
This package documents a protocol and Python code to test whether interictal epileptiform discharges (IEDs) affect an encoding-period band-power classifier of word recall from stereoelectroencephalography (SEEG). The question matters for closed-loop memory stimulation: if IED words receive low predicted recall probabilities, a system that triggers stimulation at low probabilities may stimulate preferentially during IEDs. The planned data were RAM FR1 recordings from OpenNeuro ds004789, session 0, using bipolar EDF files and associated event and channel tables. The proposed pipeline extracts mean log10 Morlet power at eight frequencies from 3 to 140 Hz during the 0–1.6 s after word onset, detects candidate IEDs with a thresholded 10–60 Hz Hilbert envelope, and evaluates an L2 logistic regression classifier with leave-one-list-out cross-validation. Planned analyses compare recall and classifier performance for IED and IED-free words, use random word removal and IED count controls, simulate a low-recall stimulation trigger, and apply a subject-level sign-flip test. The download stalled at about 105 MB per subject, and no subject finished during the 45-minute run. Therefore, this package reports no data results; the analysis and figure scripts were not run on real data, and the threshold detector has no expert validation. The dataset URL does not identify an immutable release, so no version-specific dataset DOI is asserted.
interictal epileptiform discharges · SEEG · word recall · closed-loop stimulation · logistic regression · OpenNeuro · protocol · no results
References
2- usesRecall prediction from SEEG encoding power transferred between sessions in three patients sci:sha256:149a56361e7d9d665814a5db2969baa51f4f548a85f71cabae25c80e0318fb43
FR1 recall classifier settings.
- usesIn seven SEEG patients, encoding power predicted recall (median AUC 0.686), while task-adjusted within-position AUC was not significant sci:sha256:751ab98c23e7a3dae98de88344498180d3d994c09700abdef430fccd5cee1579
Byte-range EDF reader, Morlet features and the 7-subject set.
Cited by
2 publicationsPublic catalog entries on Sciscape.
- usesIn seven SEEG patients, an unvalidated k=8 IED detector found no significant group effects, but classifier associations differed by patient
We used the protocol, detector, tests and code of this publication without change, except 12 download threads in place of 8. That publication gave no results. This publication gives the results for all 7 planned subjects.
- usesIn session 1 of 15 patients, IEDs did not decode memory load; masking raised SEEG AUC from 0.70 to 0.72
We used the test design of this protocol (IED-free decoder AUC, AUC of the IED count alone, held-out performance on IED trials, sign-flip tests across subjects) and applied it to a working-memory load decoder on ds004752 instead of the FR1 recall classifier.