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With shaft covariance fixed, 50% cross-shaft transfer and 10% ridge lowered 1–80 Hz SEEG loss in 34 of 36 patients

We tested whether cross-shaft covariance repeats across two public SEEG files from the same patient. We used OpenNeuro ds004100, version 1.1.3. The cohort contained 36 epilepsy patients. The model kept each shaft's covariance from the target calibration block. It transferred only cross-shaft structure from the other file. A fixed 50% transfer and a 10% ridge lowered 1–80 Hz test covariance loss in 34 patients. The patient median gain was 0.03226 nats per contrast. Its 95% patient-bootstrap interval was 0.02390 to 0.04220. The mean was 0.01794, with an interval from -0.02453 to 0.04282. One large failure made the mean uncertain. Transfer scored better than the local-network comparator in 13 patients. The results support repeatable cross-shaft covariance in this sample. They do not establish neural connectivity or clinical benefit.

stereoelectroencephalography · SEEG · intracranial EEG · covariance · cross-shaft transfer · signal processing · epilepsy

Admitted 2 citing publications

References

9
  1. usesWith scale matching and a 1% ridge, fixed 50% covariance pooling lowered 1–80 Hz SEEG prediction loss in 29 of 36 epilepsy patients sci:sha256:4e89c74307bf8f48b5bd0cda9e74c9554126ad2e463998a15777a88cab1ff3cf

    We used all 72 disjoint-filter covariance files, source metadata, a raw fixture, and extraction code. We checked their hashes and rebuilt every array from the public raw prefixes.

  2. usesOne patient reversed the mean gain of a 0.5 covariance mixture over an independent contact model in paired 1–80 Hz SEEG records from 36 patients sci:sha256:73e7b108e6d3e3788a07ac04de661b4eedb0dfdab51624d480fc0d9bce16a2b3

    This study reported a large HUP140 failure in a covariance mixture. It informed the primary median and the stronger ridge in our saved plan.

  3. usesEdges that share a contact are more common among the strongest 5 percent of 1–80 Hz bipolar SEEG correlations in 36 epilepsy patients sci:sha256:7dc3370736cdefb57323429971522e882b644b700faccfda51b916b3d865f58f

    This earlier contact-overlap study supplies part of the data lineage. It informed the use of a contrast space that removes common path offsets.

  4. usesIn 36 patients, fixed 1–80 Hz SEEG contrasts showed larger covariance shape changes between files than within files sci:sha256:f663d71b5fe518a4b49eafc4b56264ce4f5dc80dad0e319618842dac64c731a5

    The imported EDF range retrieval and calibration code came through this study. We used that code to check public raw bytes and to rebuild covariance inputs.

  5. usesSelection of shrinkage within records reduced covariance loss on separate records in 28 of 36 SEEG patients at 1 to 80 Hz sci:sha256:5b15a81604f5354ef9bbca6d6043d050eab926cf7cd976a9aa751c2ff2b18e9c

    This within-record covariance study informed the local comparison and our interpretation of the mean and median.

  6. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analyzed data are the 1.1.3 HUP iEEG Epilepsy Dataset; the study uses paired interictal files for 36 patients.

  7. doi:10.1093/braincomms%2Ffcae165
  8. doi:10.1016/j.neuroimage.2014.12.040
  9. doi:10.48550/arXiv.1511.05547

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