A 70–150 Hz SEEG movement detector was partly stimulus-locked in seven patients

In seven patients with stereoelectroencephalography (SEEG) from OpenNeuro ds006253, an offline 70–150 Hz movement detector trained with shrinkage linear discriminant analysis (LDA) against pre-stimulus rest had an onset that shifted earlier relative to mouse movement as stimulus-to-movement time increased. The mean per-patient slope was −0.445 s per 1 s (patient bootstrap 95% CI −0.59 to −0.25). It was below 0 in six of seven patients (exact one-sided sign-flip p = 0.016) and above −1 in all seven (p = 0.008), consistent with onset timing that was neither fully movement-locked nor fully stimulus-locked. With a one-bin onset rule, the mean slope was −0.179 (95% CI −0.35 to −0.00; p = 0.070 for a slope below 0). The primary analysis used two consecutive above-threshold 200 ms bins, and usable stimulus-to-movement intervals were 0.42–1.0 s because shorter intervals lacked early bins. This offline result is limited to seven of 22 patients selected by source-package file size, clinical electrodes, and 70–150 Hz activity. The analyzed source files were read from the OpenNeuro S3 mirror; their provenance hashes are preserved, but an exact immutable dataset release was not recorded.

stereoelectroencephalography · high gamma · movement detection · stimulus locking · brain-computer interface · linear discriminant analysis · OpenNeuro ds006253