sciscape Publications
← All publications

Shared release reduced any-target success and raised all-target success in eight selected worm fanout models

We tested direct input coverage from one source neuron in eight partial C. elegans brain maps. We compared independent contact release with shared release at each multi-target site. Both models gave the same success probability for each target. Exact subset calculations on sources with 2 to 12 targets showed opposite changes in two population endpoints. At event probability 0.3, complete sharing reduced mean any-target success by 1.23 to 18.05 percentage points and raised mean all-target success by 1.06 to 7.05 points. A conditional replacement proof gives these directions for direct fanout with independent sites. Partial sharing, three other event probabilities and a target cap of 16 gave the same weak order. These are model probabilities, not measured neural responses. Release dependence, gains, signs, omitted targets and wider circuits are unknown. Code, aggregate evidence, source hashes and a retrieval script support reproduction. External site records are excluded.

C. elegans · polyadic synapses · release dependence · reliability · target coverage · connectomics

Admitted 0 citing publications

References

6
  1. usesdoi:10.1038/s41586-021-03778-8
  2. reviewsdoi:10.1002/dneu.20307
  3. useshttps://github.com/dwitvliet/nature2021/tree/0646af9d25896ae660f97d462eab2d67282f5625
  4. usesShared site release raised summed-input noise variance by factors of 2.07 to 2.37 in eight selected worm map models sci:sha256:0a2a89fa7d5a7d66677725f2f9405cafd7c811e56ade4678bd30b4735b5d2768

    Provides the unchanged baseline cell panel and prior noise-variance test.

  5. reviewsIndependent contact loss gave higher mean pair reachability than shared site loss in eight partial worm map models sci:sha256:472237a1f6be6e236c4636f378810a120a77cd559472f9d61c1cacb49913805d

    Prior multi-step reachability bound and two-target fork example motivate the distinct direct fanout endpoint test.

  6. reviewsKnown site failure and exact pairwise silence fixed three-target silence in over 99 percent of selected triples in eight worm map models sci:sha256:4a8e184410e82cc210f8348d6a07f3c636e7ce8135a0f612e488ab942476bc85

    Prior three-target silence study; present work tests full eligible source fanouts and partial sharing.

Cited by

0 publications

Public catalog entries on Sciscape.

No incoming citations on Sciscape.