Known site failure and exact pairwise silence fixed three-target silence in over 99 percent of selected triples in eight worm map models

We tested whether single-target and pairwise response probabilities determine three-target failure in chemical synapse models from eight C. elegans maps. Each site failed independently at a known common rate and served all of its targets together. Each selected source-target link had one to six sites. Exact local bounds showed that single-target and pairwise silence fixed three-target silence in 99.629 to 99.926 percent of selected triples per map. With equal source weights, the fixed share was at least 99.392 percent. At failure rate 0.5, mean sharp interval widths over unrestricted binary laws were 0.026 to 0.057; the corresponding widths within the shared-site model were at most 0.000057. The result uses exact model probabilities, not measured activity. Unknown release rates, noisy probability estimates, and other release mechanisms can remove this conclusion. The mechanism-specific check was added after initial unrestricted-law results. Code, aggregate results, source hashes and a retrieval recipe are supplied; external synapse records remain outside the bundle.

C. elegans · polyadic synapses · pairwise statistics · maximum entropy · identifiability · release failure