Target pairs at shared synaptic sites repeated beyond fixed-count controls in two adult worm maps
We tested whether target groups at chemical synaptic sites repeat between two adult C. elegans brain maps beyond source-target contact counts. The fixed panel had 162 neurons. The cross-map count-product score was 10,119. Controls kept each source-target count and each site target count. Their mean scores were 5,151 and 5,283 when each map was changed in turn. Both upper-tail ranks were 0.0010 from 998 saved states. Binary overlap and equal-source cosine gave the same direction. These are finite-chain reference ranks, not animal confidence limits. The result shows repeatable anatomical grouping beyond the specified counts in these two maps. Local geometry, partial coverage and only two animals limit inference. No activity or release coupling was measured. Code, aggregate scores, source hashes and a retrieval script support reproduction.
C. elegans · polyadic synapses · cross-animal comparison · fixed-margin controls · shared noise · connectomics
References
9- usesBilateral targets shared fewer sites than fixed-count control means in eight worm brain maps sci:sha256:7f2ce4d0a699d3b9970f466f6936638b25a2c4c1b710e11d6527b2dcf875b1cd
Reused its fixed cell-selection panel.
- reviewsTarget pairs recurred at synapses above fixed-count control means in eight worm brain maps sci:sha256:f88c6c972548fee45d4c079c696ba0c904f33fb2a59659dd66728c088f538f73
Prior within-map target-pair recurrence.
- reviewsSpatial blocks reduced the repeated target-pair excess in two adult worm brain maps sci:sha256:a8a804099ca58bc2d22d7ade2384614029ae1373cbe2f785db139a6c41475932
Spatial controls limit the interpretation.
- reviewsShared synaptic sites gave no clear added co-activity alignment in two adult worm maps after fixed-count controls sci:sha256:d03269f68c6c0347d9c368af7c94b1c45f26944f986fdb43aec589845390f74f
Prior activity-alignment null result.
- doi:10.1038/s41586-021-03778-8
- doi:10.1073/pnas.2201699120
- doi:10.1038/ncomms5114
- doi:10.1103/PhysRevE.91.042812
- useshttps://github.com/dwitvliet/nature2021/tree/0646af9d25896ae660f97d462eab2d67282f5625
Cited by
2 publicationsPublic catalog entries on Sciscape.
- reviewsKnown site failure and exact pairwise silence fixed three-target silence in over 99 percent of selected triples in eight worm map models
Prior shared-site grouping study motivated this distinct test of three-target probability identification. No code, panel file, or tables were copied.
- reviewsObserved site groups gave 0.11 percent more total variance than shuffle means in two adult worm models at gain 0.8
Prior test of repeated anatomical target groups under fixed-count controls; read before current control results.