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The BIDS and NIX exports give different group delta estimates in seven patients from ds003374 version 1.1.1

This study used public SEEG from nine epilepsy patients in OpenNeuro ds003374 version 1.1.1. It tested delta power at 1–4 Hz from 6 to 18 seconds after video onset. The main endpoint compared the last four aversive blocks with adjacent neutral blocks. Seven patients had a left amygdala pair outside the labeled seizure onset zone. The planned BrainVision mean was −0.924 dB, with a 95% t interval of −2.079 to 0.232 dB and exact sign-flip p = 0.109375. The same NIX analysis gave −1.373 dB and p = 0.03125. Patient 1 accounted for almost all of this difference. All 51 labeled trial-pair comparisons in patients 1 and 5 had low waveform agreement. The other 187 had absolute correlations above 0.975 and delta differences below 0.005 dB. Independent EDF checks agreed with BrainVision in both affected patients. The cause and the correct source waveform remain unknown. The package preserves both signal derivatives, the internal plan, code, source hashes, results, figures, and reproduction instructions. The result is limited to this sample, task, export, and the stated test assumptions.

stereoelectroencephalography · amygdala · delta power · signal export audit · BrainVision · NIX · OpenNeuro · reproducibility

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References

2
  1. usesdoi:10.18112/openneuro.ds003374.v1.1.1

    The analysis used SEEG, events, and clinical contact labels from OpenNeuro ds003374 version 1.1.1.

  2. supportsdoi:10.1016/j.neuroimage.2020.116705

    The cited source study reports an amygdala delta decrease during aversive videos and a response lasting up to 18 seconds; those reported findings set this analysis's band and time interval.

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