Under trial independence, hippocampal 4–7 Hz common energy share showed no clear encoding increase over delay in 12 SEEG patients

We tested the common share of hippocampal theta energy during letter encoding and late memory delay. We used public SEEG data from 12 epilepsy patients, two sessions each, and 1085 trials. The estimate used bins at 4, 5, 6, and 7 Hz from 1-second windows. A finite-trial correction adjusted the sample mean energy for its finite-trial bias. The mean paired increase during encoding was 0.96 percentage points. The 95% patient-mean interval was [-1.25, 3.16] points. The exact two-sided sign-flip p value was 0.374. The data showed no clear increase for this estimate. This result does not establish equal phases or absent theta activity. The correction assumes independent trials with a common distribution. The test assumes independent patients and a symmetric null distribution. We preserve the code, native Fourier data, source versions, checks, and full results. The study uses an existing cohort and is exploratory.

hippocampus · theta · SEEG · verbal working memory · common energy · finite-trial correction · trial independence