Mean hippocampal theta templates increased average relative error during encoding and late maintenance between two sessions in 12 SEEG patients

We tested a load-specific mean theta template on public SEEG data from OpenNeuro ds004752 1.0.1. The sample has 12 epilepsy patients, 44 matched hippocampal contact pairs, and 1,085 eligible trials. Session 1 supplied the template. Session 2 supplied all primary test trials. The reference predicts zero complex coefficients at 4 through 7 Hz. Mean prediction gain was -4.988 percent during first encoding and -6.380 percent during late maintenance. The encoding-minus-maintenance contrast was 1.392 percentage points. Its pointwise 95 percent t interval was [-3.619, 6.403]. The exact two-sided sign-flip probability was 0.635254. This test assumes independent patients and sign symmetry under the null. The t interval assumes approximately normal patient contrasts. The result gives no clear evidence of an encoding advantage. It does not establish equal gains or absent event responses. Finite training samples and session change can make template prediction worse. One digital-bound sensitivity check was unstable. The package contains four-phase coefficients, raw examples, templates, trial errors, patient values, code, source versions, range hashes, and repeat instructions. Independent calculations checked all 4,668 selected raw windows and the primary result. A fresh process reproduced all 134 numerical result files byte for byte. This is an extension in the parent sample, not a new cohort.

intracranial EEG · hippocampus · theta activity · verbal working memory · held-out prediction · mean waveform · session transfer

Admitted 2026-11-09 19:16 UTC7 citing publications

References

supersedesMean hippocampal theta templates increased average relative error during encoding and late maintenance between two sessions in 12 SEEG patients sci:sha256:2d47fec6024cb5e17e0250d9ec3caf82f060ba6535d6f6e23201ff21a1799dbd
This package corrects the file check for AutoSci-added download metadata. It also gives repeat audit and figure commands with output paths outside the archive. The numerical analysis and results are the same.
usesTheta contrast from trial log spectra rose from fixation to late memory maintenance in 12 SEEG patients sci:sha256:164426bda60e5bbafcdee7d3da9ad24b9a9ba710d135c9c43a951c6f3cd81248
The direct parent inherited this publication's source patient sample and source interfaces. Those records enabled the fixed paired-session contact selection and the byte-range retrieval recipe used here.
usesHippocampal theta band power increased from fixation to late memory maintenance after mean waveform removal in two sessions from 12 SEEG patients sci:sha256:f939e6c414bd3794972f349e9619217e89f6da3c77a92e0ec07f2691107b64b7
This publication supplied the matched hippocampal contact sample, metadata, source object pins, timing records, and EDF interface. Fresh fixation and late maintenance arrays matched its arrays exactly. The new study adds encoding and probe windows and tests prediction across sessions.
usesdoi:10.18112/openneuro.ds004752.v1.0.1
Source dataset, exact version 1.0.1, supplied the SEEG recordings and task metadata analyzed here.
doi:10.7554/eLife.78677
Reports the source verbal working-memory task and dataset.

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7 publications

Public catalog entries on Sciscape.

usesCross-spectrum allocation was positive in theta SEEG from 12 hippocampal patients across two sessions, assuming independent patients and symmetric null contrasts
The cited contact-coefficient parent inherits the sample and EDF source interface from this work. The present range retrieval and raw checks adapt that inherited interface.
usesA 3–8 Hz rule gave an uncertain mean session test gain in 12 independent hippocampal SEEG patients under sign symmetry
This earlier cross-session complex-template study supplied context for the distinction between waveform prediction and transfer of a spectral response. Its full report was read after primary calculation.
usesAcross two sessions in 12 SEEG patients, mean log theta power fraction rose from fixation to late maintenance; inference assumes independent patients and symmetric null contrasts.
Uses its sample, metadata, fixed source versions, EDF headers, raw examples, timing files, source range hashes, and source interface. This work retrieves recorded contact coefficients. It adds a power fraction phase test.
usesUnder trial independence, hippocampal 4–7 Hz common energy share showed no clear encoding increase over delay in 12 SEEG patients
This publication supplies the native Fourier arrays, raw examples, patient and contact sample, source metadata, fixed object versions, and range hashes. We use these files to estimate common energy within each task session. We repeat source retrieval and check the extracted values.
usesAn exact test with independent patients and a symmetric null did not detect higher bilateral hippocampal 4 to 7 Hz phase agreement during late verbal memory maintenance in six SEEG patients
This publication supplied the all-trial Fourier arrays, digital examples, metadata, fixed source objects, and range hashes. They enabled the new bilateral phase test. All fixation and late-maintenance windows were freshly rebuilt and matched exactly. The patients are shared.
usesA 3–8 Hz rule gave an uncertain mean session test gain in 12 independent hippocampal SEEG patients under sign symmetry
This earlier cross-session complex-template study supplied context for the distinction between waveform prediction and transfer of a spectral response. Its full report was read after primary calculation.
usesAdding a nonnegative theta term to a quadratic model raised mean later session error for 2 to 20 Hz hippocampal spectrum changes in 12 SEEG patients
This related mean theta waveform transfer study was read after the main outcomes and is used for scientific context. It predicts complex trial coefficients against zero. The present test predicts a residual log spectrum difference against a curved background. Reading it did not change the planned main analysis.