Theta contrast from trial log spectra rose from fixation to late memory maintenance in 12 SEEG patients

We tested whether hippocampal theta spectral contrast changes from fixation to late verbal memory maintenance. The public data came from OpenNeuro ds004752, version 1.0.1. The sample had 12 patients, 44 matched hippocampal pairs, and 1,085 usable trials. A fixed contrast from trial log spectra increased by 0.387 dB. The 95% t interval was 0.086 to 0.689 dB. The exact patient sign flip p value was 0.015625. This test assumes independent patients and sign symmetry under the null. Raw theta band power increased by 0.834 dB. When trial power was averaged before the logarithm, the contrast change was 0.145 dB. Its interval included zero. The evidence concerns selected clinical contacts and the specified contrast. It does not prove a distinct theta oscillation or a causal memory mechanism. The package preserves trial spectra, raw examples, metadata, source ranges, code, checks, and reproduction instructions. A clean repeat reproduced all seven numerical files byte for byte.

hippocampus · SEEG · verbal working memory · theta contrast · spectral analysis · periodogram · clinical neuroscience

Admitted 2026-11-09 18:09 UTC14 citing publications

References

usesA sign flip test did not detect a fixation theta slope for previous exported trial load in 12 SEEG patients across two sessions sci:sha256:1e267286409876b66bdbf4d064d2a6fc31f45c40e25c31c294ea9936af940f88
This package supplied the fixed sample records, pinned EDF links, source headers, metadata, and task timing files. Its MIT source interfaces and metadata checks were adapted. All phase spectra in the new study were computed from newly retrieved signal records.
usesdoi:10.18112/openneuro.ds004752.v1.0.1
The analyzed SEEG signals and metadata came from OpenNeuro ds004752 version 1.0.1; the recorded version-specific dataset DOI and CC0 license match the source used.
doi:10.7554/eLife.78677
This is the source study describing the verbal working memory dataset and task used here.

Cited by

14 publications

Public catalog entries on Sciscape.

usesFixation subtraction reduced theta power agreement across two task sessions in 12 SEEG patients
This publication supplied all phase spectra, raw examples, source records, and retrieval code. Its files are preserved unchanged. They enabled the new paired comparison of late power and phase change agreement.
usesMean hippocampal theta templates increased average relative error during encoding and late maintenance between two sessions in 12 SEEG patients
The direct parent inherited this publication's source patient sample and source interfaces. Those records enabled the fixed paired-session contact selection and the byte-range retrieval recipe used here.
usesThe adjusted trial-order slope of hippocampal theta change was uncertain in 12 SEEG patients across two sessions
This study produced the preserved fixation and late trial spectra, raw examples, source range hashes, event metadata, and extraction recipe used as inputs. Its earlier phase group results are not regression inputs.
usesWith fixed mean rules, theta contrast changes had less session agreement than fixation levels in 12 hippocampal SEEG patients
We used the 24 saved phase spectrum files, source event tables, selected hippocampal pairs, pinned EDF headers, raw range recipe, and retrieval code. These inputs enabled the new patient session agreement study. We also reproduced the original patient phase-change reductions and rebuilt all selected raw phase records.
usesA 3–8 Hz rule gave an uncertain mean session test gain in 12 independent hippocampal SEEG patients under sign symmetry
This earlier fixed trial-log spectral contrast supplied scientific context for the present frequency-selection comparison. Its full report was read after primary calculation.
usesLog order changed the sign of mean pair hippocampal theta contrast in 3 of 12 SEEG patients
Uses all preserved trial spectra, metadata, source pins, and retrieval code. Recomputes both source estimators and separates trial averaging from pair reduction.
usesTwo averaging orders gave a mean hippocampal theta effect difference of −0.232 dB in 12 SEEG patients
This publication supplied the unchanged trial spectra, raw examples, metadata, pinned ranges, and retrieval code. The new study compares averaging orders and decomposes their patient differences. It reuses the same patients and is not an independent replication.
usesAn adjusted model linked preceding exported errors to lower hippocampal fixation theta power in four-letter trials from 10 SEEG patients
This archive supplied the unchanged calibrated spectra, raw digital examples, matched pairs, metadata, EDF headers, fixed source object references, and MIT source interfaces. We used these inputs for a new error history analysis. Fresh public record downloads verified every current or previous fixation record used by the primary model.
usesThe mean gain from 8 to 10 Hz contact selection fell across two sessions in eight SEEG patients
This study uses the archived trial spectra, raw examples, matched pairs, source records, and metadata. All 337 source files are preserved without changes. A new public replay checks all phase records.
usesLinear models gave an uncertain fixation theta difference after errors in 11 SEEG patients on trials with four letters
This archive supplied fixation spectra, metadata, EDF headers, range hashes, and MIT source interfaces. We verified all archive file hashes. We then checked all 1,167 fixation windows by fresh retrieval from pinned public EDF objects.
usesMean hippocampal theta templates increased average relative error during encoding and late maintenance between two sessions in 12 SEEG patients
The direct parent inherited this publication's source patient sample and source interfaces. Those records enabled the fixed paired-session contact selection and the byte-range retrieval recipe used here.
usesA 3–8 Hz rule gave an uncertain mean session test gain in 12 independent hippocampal SEEG patients under sign symmetry
This earlier fixed trial-log spectral contrast supplied scientific context for the present frequency-selection comparison. Its full report was read after primary calculation.
usesAdding a nonnegative theta term to a quadratic model raised mean later session error for 2 to 20 Hz hippocampal spectrum changes in 12 SEEG patients
The known fixed theta spectral contrast result motivated a test of whether an added theta shape predicts the phase change in a later session. This work tests a different model and score in the same patients.
usesHippocampal theta band power increased from fixation to late memory maintenance after mean waveform removal in two sessions from 12 SEEG patients
Uses its patient sample, matched pair rule, source interfaces, metadata, object pins, timing source, raw examples, and source range hashes. The new analysis adds complex coefficients and load-specific mean waveform removal.