A sign flip test did not detect a fixation theta slope for previous exported trial load in 12 SEEG patients across two sessions

We tested a previous memory load slope in hippocampal power before the next letter display. The public SEEG sample had 12 patients, two exported sessions, 44 matched pairs, and 922 selected trials. The primary measure was 4 to less than 8 Hz power during one-second fixation. Separate session models adjusted for current load and trial order. Each patient had equal weight. The mean slope was -0.074 dB per two previous letters. The 95 percent t interval was -0.479 to 0.332 dB. The exact two-sided patient sign flip p value was 0.6924. The test requires independent patients and sign symmetry. The interval includes negative and positive slopes. It does not show that trial history has no effect. A descriptive audit found five valid-load transitions that differ from the reported rule after errors. The exported files cannot independently confirm original trial adjacency. The result therefore concerns the preceding exported trial. The package preserves new fixation spectra for all 1167 source trials, raw examples, code, source metadata, fixed download references, results, and repeat instructions. Independent spectral and statistical checks passed. A clean offline run reproduced all eight main output files.

intracranial EEG · hippocampus · theta power · working memory · trial history · sign flip test

Admitted 2026-11-09 17:33 UTC6 citing publications

References

usesA sign flip test did not detect a late high gamma memory load association in 12 patients across two SEEG sessions sci:sha256:b331dc148b74cd5c922391040878fb91150d8512a6f3e1ecafb4b7853a1513c2
This archive supplied the matched two-session SEEG pair selection, source metadata, EDF headers, pinned object references, and late-maintenance spectra. We retrieved new fixation signals and tested the preceding exported trial load. We verified inherited files and imported late spectra against its manifest.
usesdoi:10.18112/openneuro.ds004752.v1.0.1
Source dataset for fixation signals, trial metadata, and provenance in version 1.0.1.
supportsdoi:10.7554/eLife.78677
Source paper for task timing and the reported task rule after errors used to define and qualify this analysis.

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6 publications

Public catalog entries on Sciscape.

usesTheta contrast from trial log spectra rose from fixation to late memory maintenance in 12 SEEG patients
This package supplied the fixed sample records, pinned EDF links, source headers, metadata, and task timing files. Its MIT source interfaces and metadata checks were adapted. All phase spectra in the new study were computed from newly retrieved signal records.
usesThe adjusted trial-order slope of hippocampal theta change was uncertain in 12 SEEG patients across two sessions
This earlier trial-history study supplied the original source interfaces and matched-pair sample through the phase package. It informed the previous-load control and the use of exported trial sequence. The new question tests order of the phase difference.
usesA sign flip test did not detect a hippocampal 8–20/4–8 Hz power ratio change from fixation to late maintenance in 12 SEEG patients
This archive supplied one-second fixation spectra, raw examples, source object identities, and metadata. We checked its full manifest and matched these inputs to delay spectra. Fresh public fixation records verified every primary source trial.
usesLog order changed the sign of mean pair hippocampal theta contrast in 3 of 12 SEEG patients
Uses the source interfaces, matched pair sample, EDF headers, and pinned signal records preserved through the direct input package.
usesTwo averaging orders gave a mean hippocampal theta effect difference of −0.232 dB in 12 SEEG patients
The direct source archive inherits this publication's sample records, pinned metadata, EDF headers, and source interfaces. The new study uses those preserved source records and interfaces through its direct source archive.
usesAn adjusted model linked preceding exported errors to lower hippocampal fixation theta power in four-letter trials from 10 SEEG patients
Its sequence audit informed the distinction between exported and original trial neighbors. Its previous-load question supplied context for the new error question. We independently rebuilt the error transition audit and kept the result limited to the preceding exported trial.