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q-bio.NC · Neurons and Cognition

The adjusted trial-order slope of hippocampal theta change was uncertain in 12 SEEG patients across two sessions

We tested whether hippocampal theta power change had a linear association with exported trial order. Public SEEG from OpenNeuro ds004752 version 1.0.1 supplied 12 patients, two sessions each, 44 matched pairs, and 981 correct trials. The response was late-maintenance minus fixation band power at 4 to less than 8 Hz, in dB. Separate session models adjusted for memory load and the previous response. The mean patient slope was -0.589 dB per exported session span. The 95% t interval was -1.895 to +0.717 dB. The exact two-sided sign-flip p value was 0.333984. The test assumes independent patients and symmetric effects under the zero null. It did not give clear evidence of a shared linear trend. The interval did not establish that the trend was zero. Fixation slopes were positive in 11 of 12 patient averages. This phase result is descriptive. The package preserves source spectra, trial measures, code, source records, all planned estimates, and reproduction instructions.

intracranial EEG · hippocampus · theta power · trial order · verbal working memory

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References

5
  1. usesFixation subtraction reduced theta power agreement across two task sessions in 12 SEEG patients sci:sha256:01f91a0084f96f0bd1b7c634ec749ac052e301ce57513937580e148b0aaabe6f

    This package supplied the unchanged phase input folder and the NumPy source replay code. The new study estimates trial-order slopes of late-minus-fixation theta power. It uses the same patient group.

  2. usesTheta contrast from trial log spectra rose from fixation to late memory maintenance in 12 SEEG patients sci:sha256:164426bda60e5bbafcdee7d3da9ad24b9a9ba710d135c9c43a951c6f3cd81248

    This study produced the preserved fixation and late trial spectra, raw examples, source range hashes, event metadata, and extraction recipe used as inputs. Its earlier phase group results are not regression inputs.

  3. usesA sign flip test did not detect a fixation theta slope for previous exported trial load in 12 SEEG patients across two sessions sci:sha256:1e267286409876b66bdbf4d064d2a6fc31f45c40e25c31c294ea9936af940f88

    This earlier trial-history study supplied the original source interfaces and matched-pair sample through the phase package. It informed the previous-load control and the use of exported trial sequence. The new question tests order of the phase difference.

  4. usesdoi:10.18112/openneuro.ds004752.v1.0.1

    The analyzed SEEG files are from OpenNeuro ds004752 version 1.0.1; saved version metadata records this DOI and CC0 license.

  5. doi:10.7554/eLife.78677

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