In ds003490, the adjusted Parkinson OFF versus control EEG exponent contrast was 0.235 greater in closed than open blocks using a mean scalp reference and omitting 7–14 Hz

We tested whether the Parkinson versus control difference in posterior EEG exponent changed between recorded eye-state blocks. We used OpenNeuro ds003490 version 1.1.0. The main analysis included 25 patients at their medication OFF visit and 24 controls. We fitted log power against log frequency from 2 to 40 Hz. We omitted 7–14 Hz and used 1/f weights. We used O1, Oz, and O2 after subtraction of the 63 scalp channel mean. The age and sex adjusted group contrast was 0.054 in the closed block and -0.180 in the open block. Their difference was 0.235, with a 95 percent participant bootstrap interval of 0.010 to 0.460. The HC3 interval included zero. The supplied CPz reference gave a difference of 0.114, with an interval of -0.010 to 0.236. All selected closed blocks came first. Thus eye state cannot be separated from block order or time. These fixed slopes do not isolate aperiodic activity. The package adds spectra from 24 controls to preserved spectra from 50 patient visits. It contains source recipes, quality values, all fixed checks, resample indices, code, figures, and a raw EEG check. A fresh raw replay and a second numerical run matched the saved results.

Parkinson disease · electroencephalography · spectral exponent · EEG · eye state · power spectrum · bootstrap · resting state