The ON minus OFF alpha reactivity interval includes zero in 25 Parkinson EEG pairs under an additive visit model without carryover
We tested posterior alpha EEG reactivity in 25 people with Parkinson disease from OpenNeuro ds003490 version 1.1.0. Each person had medication ON and OFF visits. Reactivity was the closed-eye to open-eye power ratio from 8 to below 13 Hz, in dB. We gave the two visit sequences equal weight. The ON minus OFF estimate was -0.271 dB. The 95% interval was -1.293 to 0.550 dB from 40,000 person bootstrap samples. A medication interpretation requires an additive visit effect and no carryover. All six fixed checks also gave intervals that include zero. This does not prove that medication has no effect. Source label tables disagree for one of the 25 people. A source spreadsheet supports the primary table but does not establish the true visit order. We report both label rules and a check that omits that person. The package preserves spectra, source headers and metadata, code, all scores, bootstrap samples, exact source retrieval recipes, and validation records. A full-file source check and an independent reader check passed. A fresh analysis reproduced all 12 numerical result files byte for byte. The evidence applies to the tested sample, signal method, and recorded medication labels.
Parkinson disease · electroencephalography · alpha reactivity · medication · EEG · bootstrap interval
References
2- usesdoi:10.18112/openneuro.ds003490.v1.1.0
Source EEG, event times, participant labels, and source label tables for OpenNeuro ds003490 version 1.1.0.
- doi:10.1177/15459683251347631
Background study motivating an ON and OFF alpha-reactivity comparison; its normalized metric differs from the absolute-power ratio analyzed here.
Cited by
4 publicationsPublic catalog entries on Sciscape.
- usesThe ON minus OFF interval for the closed-eye posterior theta-to-alpha EEG ratio includes zero in 25 Parkinson pairs under an additive visit model without carryover
This study uses the posterior EEG window spectra, source metadata, selected rest blocks, visit labels, raw-range hashes, and retrieval code. We checked the imported spectra against the original signals. We calculated a new theta-to-alpha outcome and matched acceleration measures. No parent medication estimate enters the new estimates.
- usesFixed 28-second ridge fits of hand acceleration increased mean later 4–8 Hz posterior EEG error during closed-eye rest in 25 ds003490 v1.1.0 Parkinson participants
Its MIT retrieval code was supplied through the parent package. We adapted that code to require saved range hashes and to preserve the new download log. The original license is included.
- usesIn ds003490, the adjusted Parkinson OFF versus control EEG exponent contrast was 0.235 greater in closed than open blocks using a mean scalp reference and omitting 7–14 Hz
This work reused unchanged spectra and quality arrays from 50 patient visits. It also used the inspected source extractor, retriever, metadata, and label audit. New control spectra were extracted with the same code.
- usesadjusted Parkinson OFF versus control posterior EEG exponent contrast was 0.235 greater in closed than open blocks in ds003490. The fit used a mean scalp reference and omitted 7–14 Hz from 2–40 Hz.
This work reused unchanged spectra and quality arrays from 50 patient visits. It also used the inspected source extractor, retriever, metadata, and label audit. New control spectra were extracted with the same code.