Window power normalization reduced mean file slope differences in paired 60 s bipolar SEEG records from 36 patients, with a 30 to 80 Hz fit and 55 to 65 Hz removed

We tested window power normalization in public SEEG data from OpenNeuro ds004100, version 1.1.3. We used two 60 s interictal excerpts from each of 36 patients and 3,686 named adjacent bipolar pairs. Each 2 s window spectrum was divided by its power in the fit band before we averaged the spectra. The fit used 30 to 80 Hz and removed 55 to 65 Hz. Each patient score was the median absolute exponent difference between files. The mean score fell from 0.17344 to 0.14932 units. The mean gain was 0.02412 units, or 13.91 percent. The 95 percent patient bootstrap interval was 0.01665 to 0.03263 units. This interval assumes independent and exchangeable patients. Scores fell in 31 patients and rose in five. All nine fixed sensitivity checks had positive mean gains. The spatial interquartile range fell. The range-scaled score fell and rank agreement rose. Normalization changed the exponent values and the measured quantity. The evidence shows smaller observed file differences, without a known biological target for accuracy. The biological gap between files is unknown. This analysis reuses a prior cohort. The package preserves full spectra, window summaries, code, fixed plans, source versions and hashes, results, checks, figures, and reproduction instructions.

stereoelectroencephalography · SEEG · spectral slope · power normalization · file agreement · intracranial EEG

Admitted 2026-11-09 18:37 UTC2 citing publications

References

usesMedian Welch spectra gave smaller mean file differences for 30–80 Hz exponents in paired 60 s bipolar SEEG records from 36 patients, with 55–65 Hz removed sci:sha256:82d34593ca70a122d42ce91c4739ff2a3d3cc696d375a051587e30a33d29ab60
We used this fixed cohort, contact lists, raw retrieval recipe, full mean and median spectra, and comparator results. We rebuilt all raw inputs and checked the inherited spectra before the new normalization comparison.
usesCommon average reference raises median relative gamma rank agreement in two 60 s SEEG records from each of 36 HUP patients sci:sha256:3f5f9f6ae779730a7bf70359ae9ddc56a5032c2e8abdb97c0cf3c127d6082e74
We used the original cohort and contact selection inherited through the parent publication. This is the same selected patient cohort, not an independent replication.
usesMean bipolar reference effects exceeded file differences for 30–80 Hz slopes in paired 60 s SEEG records from 36 patients sci:sha256:a343645ba027d704e981c68fea0352745ba1410c491d9bbbcc42ef099ff50447
We used the inherited MIT source code, adjacent pair rules, raw source identities, file timing, and overlap audit. These items enabled the version-pinned rebuild and the stated limits on file timing.
usesdoi:10.18112/openneuro.ds004100.v1.1.3
Source data: OpenNeuro ds004100, version 1.1.3, used for the 36-patient SEEG cohort and recordings.

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usesEqual window power reduced file disagreement but did not establish better seizure onset label ranking in 31 patients
This source supplied the frozen spectra, public metadata, contact geometry, raw download recipe, and spectrum build code. Its file agreement result motivated the new clinical label ranking test. All 72 raw extracts were retrieved again, and all 504 compact arrays were rebuilt exactly.
usesWindow power normalization gave an onset AUC change interval that included zero for 30–80 Hz bipolar SEEG in 31 patients
We used its frozen 36-patient SEEG cohort, normalized and ordinary spectra, source metadata, pinned signal retrieval recipe, and raw processing code. These files supported the new paired onset ranking test and the complete raw rebuild.