Mean bipolar reference effects exceeded file differences for 30–80 Hz slopes in paired 60 s SEEG records from 36 patients

1. usesCommon average reference raises median relative gamma rank agreement in two 60 s SEEG records from each of 36 HUP patients sci:sha256:3f5f9f6ae779730a7bf70359ae9ddc56a5032c2e8abdb97c0cf3c127d6082e74

   We used the fixed HUP source cohort, retained contact lists, source metadata, frozen raw hashes, retrieval code, and EDF reader. Fresh downloads and new paired bipolar spectra enabled the reference-versus-file comparison.

2. usesAdjacent bipolar subtraction reduced median 30 to 80 Hz log power exponents relative to common average spectra in two resting SEEG records sci:sha256:d3e7e07f1b7d0184f72f7df76720eba1adbcad9be3157162ca1096368a315f13

   The prior two-record study supplied the reference-slope question and mean cross-spectrum identity. We tested a larger, different epilepsy cohort and added patient-level file and half-record comparisons.

3. usesCommon average 30–80 Hz spectral slopes had mean onset-label AUC of 0.473 in paired 60 s SEEG records from 36 patients sci:sha256:9fd58699b965345c851b5361a87b4b86fb623db5b74a0d38c20a5039bde188a3

   The prior CAR-only slope analysis of this HUP cohort informed the study scope. This study adds paired bipolar spectra and a reference-versus-file contrast. We did not reuse its power values or test clinical labels.

4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

   The study analyzed the first 60 seconds of two interictal SEEG files per patient from OpenNeuro ds004100 version 1.1.3.

5. doi:10.1016/j.neuroimage.2018.08.020
6. doi:10.1038/s41593-020-00744-x

Public catalog entries on Sciscape.

• usesQuadratic log-frequency fits gave lower spectral shape error than straight fits in separate bipolar SEEG files from 36 patients at 20–100 Hz with 55–65 Hz removed

  The fetched spectral package contains retrieval, EDF decode, and contact-rule code from this publication. We preserved that code and used it for the fresh raw reconstruction.

• usesBipolar reference gave higher mean onset AUC than CAR for 30 to 80 Hz SEEG pair slopes within shafts in 31 patients with stable, matching contact marks

  Supplied all 36 paired spectrum archives, source metadata, retained contact lists, adjacent pair maps, frozen raw hashes, and the retrieval and spectral code used in the new onset rank comparison.

• uses30 to 80 Hz bipolar slope maps retained mean correlation 0.841 after linear shaft trend removal in paired 60 s files from 33 SEEG patients

  We used the paired spectra, fixed contact list, extraction methods, and raw retrieval pins. We rebuilt all 504 spectrum arrays. We tested agreement after shaft trend removal.

• usesNominal 95 percent intervals on mean 30 to 80 Hz band slopes had lower coverage in other files from 36 SEEG patients

  We used its fixed 36 patient cohort, retained contacts, raw retrieval recipe, EDF reader, and adjacent pair and slope fit functions. We computed new time block slopes and prediction interval coverage.

• usesA bounded power law plus a constant floor reduced mean spectral shape error against straight fits in separate bipolar SEEG records from 36 patients at 20–100 Hz with 55–65 Hz removed

  The inherited retrieval, EDF decode, and contact-rule code came from this work through the fetched spectral package. We inspected and used that code for the fresh raw reconstruction.

• uses30 to 80 Hz bipolar slope maps retained mean correlation 0.841 after linear shaft trend removal in paired 60 s files from 33 SEEG patients

  We used the paired spectra, fixed contact list, extraction methods, and raw retrieval pins. We rebuilt all 504 spectrum arrays. We tested agreement after shaft trend removal.

• usesA bounded power law plus a constant floor reduced mean spectral shape error against straight fits in separate bipolar SEEG records from 36 patients at 20–100 Hz with 55–65 Hz removed

  The inherited retrieval, EDF decode, and contact-rule code came from this work through the fetched spectral package. We inspected and used that code for the fresh raw reconstruction.

• usesA three-factor allocation with mean anchors gave coherency magnitude the larger absolute CAR-to-bipolar exponent term in 36 SEEG patients (30–80 Hz; 55–65 Hz omitted)

  This earlier fixed CAR and bipolar slope comparison motivates the reference exponent question. The new test retains its sample and spectral choices through the immediate source. It tests a new magnitude and phase cosine allocation, without adding an independent cohort.

• usesContact group corrections reduced mean theta to high gamma ratio error compared with shaft corrections in paired 60 second SEEG excerpts from 36 patients

  The fixed retained contact order and EDF retrieval methods came from this study through the span study. We preserved the imported code license and retained the cohort without new selection.

• usesMedian Welch spectra gave smaller mean file differences for 30–80 Hz exponents in paired 60 s bipolar SEEG records from 36 patients, with 55–65 Hz removed

  We used the fixed 36-patient cohort, contact lists, compact spectra, source records, and MIT retrieval and slope code. We rebuilt all 72 raw prefixes and checked their spectra against this source. The new analysis compares mean and median file differences and adds full 20–100 Hz median spectra.

• usesA symmetric split gave real coherency the larger absolute CAR to bipolar slope term in 30–80 Hz SEEG fits from 36 patients

  We used its fixed 36-patient sample, 72 excerpt pins, retained contacts, adjacent pair rules, and reference powers. We rebuilt the spectra and added contact powers and real cross spectra to test the two-factor split.

• usesPaired bipolar SEEG spectra gave expected balanced accuracy above chance for stable random pair labels in 36 patients

  We used its 36 paired spectrum archives, fixed contact selection, source metadata, and retrieval code. These inputs enabled the new random pair label audit. All 72 source excerpts were retrieved again and all spectrum arrays were rebuilt.

• usesResidual spectral shape matched 13 of 36 SEEG record pairs from the same implants within sample rate groups

  We used the inherited MIT EDF reader and raw retrieval recipe through the direct input publication. Fresh retrieval checked all 72 source prefixes.

• usesA floor model gave lower mean error than a positive knee in paired bipolar SEEG from 36 patients at 20–100 Hz with 55–65 Hz removed

  This work supplied the retained contact lists and MIT code for raw file retrieval, EDF reading, and contact pairing.

• usesWindow power normalization reduced mean file slope differences in paired 60 s bipolar SEEG records from 36 patients, with a 30 to 80 Hz fit and 55 to 65 Hz removed

  We used the inherited MIT source code, adjacent pair rules, raw source identities, file timing, and overlap audit. These items enabled the version-pinned rebuild and the stated limits on file timing.

• usesLocal 50% bipolar SEEG spectral pooling did not establish lower mean error in 36 patients

  We reused the contact conventions and MIT-licensed raw retrieval and EDF methods preserved through the cited input package. The publication package preserves the imported code and license.

• usesThree interval bipolar spans increased theta to high gamma ratios in paired 60 second SEEG excerpts from 36 patients

  We used its fixed patient cohort, contact order, pinned raw retrieval locks, and retrieval code. We calculated new bipolar span spectra from the public raw bytes.

• usesPatient calibration covered all 17 test SEEG slope maps at 30 to 80 Hz with nominal 90 percent bands 7.56 times wider than pointwise bands

  We used its fixed source manifest, contact list, and raw retrieval recipe as preserved in the cited block slope study.

• uses30 to 80 Hz bipolar slope maps retained mean correlation 0.841 after linear shaft trend removal in paired 60 s files from 33 SEEG patients

  We used the paired spectra, fixed contact list, extraction methods, and raw retrieval pins. We rebuilt all 504 spectrum arrays. We tested agreement after shaft trend removal.