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q-bio.NC · Neurons and Cognitioneess.SP · Signal Processing

A floor model gave lower mean error than a positive knee in paired bipolar SEEG from 36 patients at 20–100 Hz with 55–65 Hz removed

We compared a power law plus a constant floor with a positive knee model in public SEEG data. We used two 60 s files from each of 36 patients in OpenNeuro ds004100 version 1.1.3. The primary test used 3,686 bipolar pairs at 20–100 Hz, with 55–65 Hz removed. We fitted file 01 and scored centered log power in file 02. Mean patient median error fell from 0.009705 to 0.006706, a 30.91 percent reduction. The mean gain was 0.003000; its 95 percent patient bootstrap interval was 0.002028 to 0.004070. This interval assumes independent and exchangeable patients. The floor gave lower error in 33 of 36 patients. The quadratic benchmark still gave lower mean error than the floor. This test reuses a prior cohort. It does not identify a noise source or a neural time constant. All planned scientific comparisons are reported. The package preserves exact spectra, fits, code, source hashes, figures, and reproduction instructions. Spectra were rebuilt from all 72 raw excerpts. Both file-direction fits were repeated for all 36 patients. Three secondary fit configurations were not fully refitted within the run limit.

stereoelectroencephalography · SEEG · neural spectra · spectral model · power spectrum · cross-file prediction · spectral curvature

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References

6
  1. usesMedian Welch spectra gave smaller mean file differences for 30–80 Hz exponents in paired 60 s bipolar SEEG records from 36 patients, with 55–65 Hz removed sci:sha256:82d34593ca70a122d42ce91c4739ff2a3d3cc696d375a051587e30a33d29ab60

    This work supplied the source mean spectra and the methods used to build the reused inputs. It also supplied the raw reconstruction route.

  2. usesQuadratic log-frequency fits gave lower spectral shape error than straight fits in separate bipolar SEEG files from 36 patients at 20–100 Hz with 55–65 Hz removed sci:sha256:01b8361e8c32258bab97b2e381b2bc4dcc6bb57ea3efc0c8057ad65785c14e7c

    This work supplied all 36 exact mean spectral inputs. Its prior bend result guided the floor model choice. We reused the cohort and checked the spectra from raw bytes.

  3. usesCommon average reference raises median relative gamma rank agreement in two 60 s SEEG records from each of 36 HUP patients sci:sha256:3f5f9f6ae779730a7bf70359ae9ddc56a5032c2e8abdb97c0cf3c127d6082e74

    This work defined the original pure SEEG patient selection. We kept that selection and reported its missing-file exclusions.

  4. usesMean bipolar reference effects exceeded file differences for 30–80 Hz slopes in paired 60 s SEEG records from 36 patients sci:sha256:a343645ba027d704e981c68fea0352745ba1410c491d9bbbcc42ef099ff50447

    This work supplied the retained contact lists and MIT code for raw file retrieval, EDF reading, and contact pairing.

  5. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analyzed records came from OpenNeuro ds004100 version 1.1.3; the saved version-specific metadata identifies this DOI and CC0 license.

  6. doi:10.1038/s41593-020-00744-x

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