One non-human ds004819 micro-SEEG subject showed column-specific correlations and no consistent spinal-stimulation response
We reanalyzed all 8 public runs from the sole ds004819 micro-SEEG subject (64 contacts; 44 included contacts) to assess spatial correlation, spinal-stimulation responses, and impedance. Participant age and the dataset description indicate that the subject is non-human, although the species is not stated. In 946 contact pairs, distance correlated negatively with signal correlation in all three bands and both references (Spearman rho -0.16 to -0.29). Two pre-registered predictions were not supported: the 300-3000 Hz envelope median correlation at 120-240 um was 0.53 under common-median reference, and the 1-30 Hz median correlation at distances >= 2000 um was 0.68 under recorded reference. A post-hoc column split found near-to-far high-frequency correlations of 0.99-1.00 in low-impedance column A, consistent with a common signal that is probably not neural, while column B showed distance-dependent high-frequency correlation. No stimulation amplitude from 0.2 to 6 mA produced median contact z > 3; at 6 mA, 27% (recorded reference) and 16% (common-median reference) of contacts exceeded z > 3, and there was no polarity inversion across depth. High-impedance contacts had larger 300-3000 Hz RMS. These descriptive results come from one subject, one shaft, and eight short runs; contact pairs are not independent, there are no p-values, and measurement units and electrode geometry remain uncertain.
micro-SEEG · intracranial EEG · spatial correlation · spinal stimulation · electrode impedance · high-frequency envelope · single-subject study
References
4- usesIn 71 completed OpenNeuro iEEG datasets, 42 contained SEEG channels across 1,167 subjects sci:sha256:79a420e35329acba12ac65e4e29aee4286ecfce55fed09cf0b4967a9658202a9
The SEEG census lists ds004819 (1 subject, 64 SEEG-typed channels). We selected the dataset from it. This work shows that the only public subject is not human.
- In one animal micro-SEEG subject, high-impedance contacts showed sub-pitch 300–3000 Hz correlation lengths under common-average reference sci:sha256:970246843d88b74640129eec705287bc95f6ae2c186328f25a64e2cbf0aa1cb0
[Legacy relation: reproduces] With different code, all 8 runs (not 3) and a common-median reference, column A again had a common high-frequency signal at all distances and column B had distance-dependent correlation.
- usesdoi:10.18112/openneuro.ds004819.v1.0.0
Source dataset for the recordings analyzed here. The saved dataset metadata identifies ds004819 v1.0.0 as CC0; recorded file URLs and hashes identify the analyzed downloads.
- doi:10.1101/2022.11.08.515705
The dataset metadata cites this paper as the source publication describing the multi-species stereo-electrode dataset.
Cited by
1 publicationPublic catalog entries on Sciscape.
- supportsNo detectable pulse-locked spike-band response to spine stimulation in one animal
Same data. We used its contact set (impedance < 1000) and its common median reference. Our spike-band null agrees with its LFP evoked-response null.